Anti-OPRD1 Polyclonal Antibody – Cat# MBS352198

Opioid Receptor Delta IgG Fraction (OPRD1) Antibody – Polyclonal

Name: OPRD1 Antibody; Polyclonal; MyBioSource
Brand: MyBioSource
SKU: MBS352198
Price: 780 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS352198

This IgG fraction was prepared by precipitation. dialysis and chromatography from an antiserum that was raised in a rabbit which was immunized with a peptide analogue of the carboxyl terminal of the delta opioid receptor covalently attached onto a carrier… More details

$780 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Opioid Receptor Delta IgG fraction (OPRD1), Polyclonal Antibody

Full Product Name

Opioid Receptor Delta IgG fraction

Product Gene Name

anti-OPRD1 antibody

Product Synonym Names

Opioid Delta Receptor (360-372); IgG Fraction of Rabbit Anti-Delta Opioid Receptor Serum

Clonality

Polyclonal

Form/Format

Antiserum Specificity

Specificity

Polypeptide ::: % Cross Reactivity
Delta Opioid Receptor (360-372) ::: 100
Delta Opioid Receptor ::: 60

Molecular Weight

40238 Da

Chromosome Location

Chromosome: 1; NC_000001.10 (29138654..29190208). Location: 1p36.1-p34.3

OMIM

165195

3D Structure

ModBase 3D Structure for P41143

Product Categories/Family for anti-OPRD1 antibody

Histochemical Grade Antibodies; Opioid Receptor Antibodies and Kits

Applications Tested/Suitable for anti-OPRD1 antibody

Immunocytochemical Staining, Western Immunoblot, Western Blot

Application Notes for anti-OPRD1 antibody

Immunocytochemistry: This IgG fraction has been found to stain specific cells in various regions of PLP fixed rat brain sections known to express the delta opioid receptor using ABC techniques at a concentration of 20 ug per ml..

Western Blot: Western immunoblots using whole rat brain homogenate have been successful at a concentration of 50 ug per ml.

Western Blot Protocol: 1. After SDS-PAGE (on either 4-15% gradient gels or single percentage gels. such at 12% gels) and electrophoretic transfer to PVDF membrane. block the membrane overnight with 2% normal goat serum in TBS/Tween-20 buffer.
2. Wash x 2 with TBS/Tween-20.
3. Apply the IgG fraction after dilution to at least 50 ugm per ml (Note: higher dilutions may be needed). Use 2% normal goat serum in TBS/Tween-20 as buffer for the primary antibody. Let the primary antibody bind for 2-4 hours.
4. Wash x 3 with TBS/Tween-20.
5. Apply affinity purified HRP-goat anti-rabbit IgG antiserum diluted 1:2500 (dilution may vary depending upon supplier) in 2% normal goat serum in TBS/Tween-20. Incubate 1-2 hours. Note: greater sensitivity may be achieved using ABC techniques.
6. Wash x 4 for 5 minute/wash with TBS/Tween-20.
7. Develop color using the enhanced DAB reaction.

Other Notes

Small volumes of anti-OPRD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OPRD1 purchase

MBS352198 is an antibody targeting OPRD1. Also known as Opioid Receptor Delta IgG fraction.

Additional Details

NCBI/Uniprot data below describe general gene information for OPRD1. It may not necessarily be applicable to this product.

NCBI GI #

63477962

NCBI GeneID

4985

NCBI Accession #

NP_000902.3

UniProt Primary Accession #

P41143

UniProt Secondary Accession #

B5B0B8

UniProt Related Accession #

P41143

GenBank Nucleotide #

NM_000911.3

NCBI Official Full Name

delta-type opioid receptor

NCBI Official Synonym Full Names

opioid receptor, delta 1

NCBI Official Symbol

OPRD1

NCBI Official Synonym Symbols

OPRD

UniProt Protein Name

Delta-type opioid receptor

UniProt Synonym Protein Names

DOR-1

Protein Family

Delta-type opioid receptor

UniProt Gene Name

OPRD1

UniProt Synonym Gene Names

OPRD

UniProt Entry Name

OPRD_HUMAN

NCBI Protein Information

delta-type opioid receptor; DOR-1; D-OR-1; OTTHUMP00000003778; delta opioid receptor 1

UniProt Comments for OPRD1

Function: Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. receptor for enkephalins.

Subunit structure: Interacts with GPRASP1. Ref.6 Ref.7

Subcellular location: Cell membrane; Multi-pass membrane protein.

Sequence similarities: Belongs to the G-protein coupled receptor 1 family.

Research Articles on OPRD1

1. data suggest that an increased constitutive internalization and/or concurrent signaling of the delta-opioid receptor-Cys27 variant affects APP processing through altered endocytic trafficking of APP

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-OPRD1 antibody

Reference Product	PubMed Publications
OPRM1 antibody	>17 publications with OPRD1 and OPRM1
OPRK1 antibody	>12 publications with OPRD1 and OPRK1
GNAZ antibody	>1 publications with OPRD1 and GNAZ
ARRB2 antibody	>1 publications with OPRD1 and ARRB2

Pathways associated with anti-OPRD1 antibody

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Peptide GPCRs Pathway antibodies	Peptide GPCRs Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram

Diseases associated with anti-OPRD1 antibody

Disease Name	Pubmed Publications
Pain Antibodies	>9 publications with OPRD1 and Pain
Autistic Disorder Antibodies	>1 publications with OPRD1 and Autistic Disorder
Child Development Disorders, Pervasive Antibodies	>1 publications with OPRD1 and Child Development Disorders, Pervasive
Anxiety Disorders Antibodies	>1 publications with OPRD1 and Anxiety Disorders
Hepatitis Antibodies	>1 publications with OPRD1 and Hepatitis

Organs/Tissues associated with anti-OPRD1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>7 publications with OPRD1 and Brain