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SGI-1776

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600114

SGI-1776 is a potent, selective, orally active Pim kinase inhibitor with IC50 of 7, 363 and 69 nM for Pim1, Pim2 and Pim3, respectively. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SGI-1776, Biochemical
Full Product Name
SGI-1776
Product Synonym Names
SGI 1776; SGI1776
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
405.42
Suitability
10mM in DMSO
Target
Pim
Receptor
FLT3; Pim1; Pim2; Pim3
Chemical Name
Imidazo[1, 2-b]pyridazin-6-amine, N-[(1-methyl-4-piperidinyl)methyl]-3-[3-(trifluoromethoxy)phenyl]
SMILES
FC(F)(F)OC1=CC=C(C2=CN=C3C=CC(NCC4CCN(C)CC4)=NN32)C=C1
Molecular Formula
C20H22F3N5O
CAS Number
1025065-69-3

Product Categories/Family for SGI-1776 biochemical

Prostate Cancer; JAK/STAT Signaling; Cancer

Structure of SGI-1776 biochemical

SGI-1776 Biochemical – Cat# MBS3600114

Product References and Citations for SGI-1776 biochemical

1. Chen LS, et al. Blood. 2009 Nov 5; 114 (19):4150-7.
2. Chen LS, et al. Blood. 2011 Jul 21; 118 (3):693-702.
3. Chang M, et al. Mol Cancer Ther. 2010 Sep; 9 (9):2478-87.
4. Mumenthaler SM, et al. Mol Cancer Ther. 2009 Oct; 8 (10):2882-93.

Other Notes

Small volumes of SGI-1776 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SGI-1776 purchase

MBS3600114 is a biochemical targeting SGI-1776.
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