Edicotinib (JNJ 40346527)

Name: Edicotinib (JNJ 40346527); MyBioSource
Brand: MyBioSource
SKU: MBS3600505
Price: 265 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600505

Edicotinib (JNJ 40346527, PRV 6527) is a potent, selective, orally bioavailable CSF-1R inhibitor with IC50 of 3.2 nM; shows weak affinity for KIT and FLT3 (IC50= 20 nM and 190 nM, respectively). More details

$265 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Edicotinib, Biochemical

Full Product Name

Edicotinib

Product Synonym Names

JNJ 40346527; PRV 6527

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

461.61

Suitability

DMSO: 16.67mg/mL (36.11mM)
H2O: <0.1mg/mL

Target

CSF1R

Receptor

CSF1R

Chemical Name

4-cyano-N-[2-(4, 4-dimethylcyclohex-1-en-1-yl)-6-(2, 2, 6, 6-tetramethyloxan-4-yl)pyridin-3-yl]-1H-imidazole-2-carboxamide

SMILES

O=C(C1=NC(C#N)=CN1)NC2=CC=C(C3CC(C)(C)OC(C)(C)C3)N=C2C4=CCC(C)(C)CC4

Molecular Formula

C27H35N5O2

CAS Number

1142363-52-7

Product Categories/Family for Edicotinib biochemical

Rheumatoid Arthritis; Tyrosine Kinase; Inflammation/Immunology

Product References and Citations for Edicotinib biochemical

1. von Tresckow B, et al. Clin Cancer Res. 2015 Apr 15; 21 (8):1843-50.
2. Genovese MC, et al. J Rheumatol. 2015 Oct; 42 (10):1752-60.
3. Pass HI, et al. Oncotarget. 2016 Aug 30; 7 (35):56408-56421.

Other Notes

Small volumes of Edicotinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Edicotinib purchase

MBS3600505 is a biochemical targeting Edicotinib.