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BMS-911543

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601136

MBS3601136 is a biochemical targeting BMS-911543. A potent and selective small-molecule inhibitor of JAK2 with IC50 of 1.1 nM. More details

$285 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BMS-911543, Biochemical
Full Product Name
BMS-911543
Product Synonym Names
BMS911543; BMS 911543
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
432.5214
Suitability
10mM in DMSO
Target
JAK
Receptor
JAK1; JAK2; JAK3; SET-2; Tyk2
Chemical Name
Imidazo[4, 5-d]pyrrolo[2, 3-b]pyridine-7-carboxamide, N, N-dicyclopropyl-4-[(1, 5-dimethyl-1H-pyrazol-3-yl)amino]-6-ethyl-1, 6-dihydro-1-methyl
SMILES
CCN1C(=CC2=C3C(=C(N=C21)NC4=NN(C(=C4)C)C)N=CN3C)C(=O)N(C5CC5)C6CC6
Molecular Formula
C23H28N8O
CAS Number
1271022-90-2

Product Categories/Family for BMS-911543 biochemical

Bone Cancer; Angiogenesis; Cancer

Structure of BMS-911543 biochemical

BMS-911543 Biochemical – Cat# MBS3601136

Product References and Citations for BMS-911543 biochemical

1. Purandare AV, et al. Leukemia. 2012 Feb; 26 (2):280-8.
2. Wan H, et al. ACS Med Chem Lett. 2015 Jul 12; 6 (8):850-5.
3. Mace TA, et al. Oncotarget. 2015 Dec 29; 6 (42):44509-22.

Other Notes

Small volumes of BMS-911543 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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