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Avacopan (CCX-168)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601405

Avacopan (CCX-168, CCX168) is a potent, selective, orally availale C5aR (CD88) inhibitor with IC50 of 0.1 nM. More details

$255 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Avacopan, Biochemical
Full Product Name
Avacopan
Product Synonym Names
CCX-168; CCX168
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
581.656
Suitability
DMSO: >=10.1mg/mL (17.36mM)
H2O: <0.1mg/mL
Target
Complement System
Receptor
Complement System
Chemical Name
(2R, 3S)-2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6-methylbenzoyl)-N-(4-methyl-3-(trifluoromethyl)phenyl)piperidine-3-carboxamide
SMILES
O=C([C@@H]1[C@H](C2=CC=C(NC3CCCC3)C=C2)N(C(C4=C(C)C=CC=C4F)=O)CCC1)NC5=CC=C(C)C(C(F)(F)F)=C5
Molecular Formula
C33H35F4N3O2
CAS Number
1346623-17-3

Structure of Avacopan biochemical

Avacopan CCX-168 Biochemical – Cat# MBS3601405

Product References and Citations for Avacopan biochemical

1. Xiao H, et al. J Am Soc Nephrol. 2014 Feb; 25 (2):225-31.
2. Bekker P, et al. PLoS One. 2016 Oct 21; 11 (10):e0164646.
3. Jayne DRW, et al. J Am Soc Nephrol. 2017 Sep; 28 (9):2756-2767.

Other Notes

Small volumes of Avacopan biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Avacopan purchase

MBS3601405 is a biochemical targeting Avacopan.
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