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THZ2

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602304

THZ2, an analogue of THZ1 with improved pharmacokinetic features, is a potent, selective CDK7 inhibitor with IC50 of 13.9 nM, displays a 5-fold improved half-life in vivo compared with THZ1. More details

$310 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
THZ2, Biochemical
Full Product Name
THZ2
Product Synonym Names
THZ-2
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
566.0527
Suitability
DMSO: >=39mg/mL
Target
CDK
Receptor
CDK
Chemical Name
Benzamide, N-[3-[[5-chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-3-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]
SMILES
O=C(NC1=CC=CC(NC2=NC=C(Cl)C(C3=CNC4=C3C=CC=C4)=N2)=C1)C5=CC=CC(NC(/C=C/CN(C)C)=O)=C5
Molecular Formula
C31H28ClN7O2
CAS Number
1604810-84-5

Product Categories/Family for THZ2 biochemical

Angiogenesis; Cancer

Product References and Citations for THZ2 biochemical

1. Wang Y, et al. Cell. 2015 Sep 24; 163 (1):174-86.

Other Notes

Small volumes of THZ2 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for THZ2 purchase

MBS3602304 is a biochemical targeting THZ2.
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