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PF-06426779

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602792

PF-06426779 (PF06426779) is a potent, selective IRAK4 inhibitor with IC50 of 1 nM against full-length IRAK4 kinase and cell-based IC50 of 12 nM. More details

$680 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PF-06426779, Biochemical
Full Product Name
PF-06426779
Product Synonym Names
PF06426779
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
347.346
Target
IRAK
Receptor
IRAK
Chemical Name
1-(((2S, 3S, 4S)-4-Fluoro-3-methyl-5-oxopyrrolidin-2-yl)methoxy)-7-methoxyisoquinoline-6-carboxamide
SMILES
CC1C(NC(=O)C1F)COC2=NC=CC3=CC(=C(C=C32)OC)C(=O)N
Molecular Formula
C17H18FN3O4
CAS Number
1817628-40-2

Product References and Citations for PF-06426779 biochemical

1. De Nardo D, et al. J Biol Chem. 2018 Aug 3. pii: jbc.RA118.003314.
2. Lee KL, et al. J Med Chem. 2017 Jul 13; 60 (13):5521-5542.

Other Notes

Small volumes of PF-06426779 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-06426779 purchase

MBS3602792 is a biochemical targeting PF-06426779.
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