Sitaxsentan (IPI-1040)

Name: Sitaxsentan (IPI-1040); MyBioSource
Brand: MyBioSource
SKU: MBS3602843
Price: 770 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602843

A potent, long acting, orally active, selective ETA receptor antagonist that binds competitively to human ETA receptor with Ki of 0.43 nM, IC50 of 1.4 nM. More details

$770 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Sitaxsentan, Biochemical

Full Product Name

Sitaxsentan

Product Synonym Names

IPI-1040; Sitaxentan; TBC-11251

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

454.9045

Suitability

10mM in DMSO

Target

Endothelin Receptor

Receptor

Endothelin Receptor

Chemical Name

3-Thiophenesulfonamide, N-(4-chloro-3-methyl-5-isoxazolyl)-2-[2-(6-methyl-1, 3-benzodioxol-5-yl)acetyl]

SMILES

CC1=CC2=C(C=C1CC(=O)C3=C(C=CS3)S(=O)(=O)NC4=C(C(=NO4)C)Cl)OCO2

Molecular Formula

C18H15ClN2O6S2

CAS Number

184036-34-8

Product Categories/Family for Sitaxsentan biochemical

Hypertension; GPCR/G Protein; Cardiovascular Disease

Product References and Citations for Sitaxsentan biochemical

1. Wu C, et al. J Med Chem. 1997 May 23; 40 (11):1690-7.
2. Wanebo JE, et al. Neurosurgery. 1998 Dec; 43 (6):1409-17; discussion 1417-8.
3. Tilton RG, et al. Pulm Pharmacol Ther. 2000; 13 (2):87-97.

Other Notes

Small volumes of Sitaxsentan biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Sitaxsentan purchase

MBS3602843 is a biochemical targeting Sitaxsentan.