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PNU-159682

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603151

A highly potent metabolite of the anthracycline nemorubicin with outstanding cytotoxicity; a topoisomerase inhibitor and ADCs cytotoxin. More details

$340 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PNU-159682, Biochemical
Full Product Name
PNU-159682
Product Synonym Names
PNU159682; PNU 159682
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
641.6192
Suitability
10mM in DMSO
Target
ADC Cytotoxin
Receptor
ADC Cytotoxin
Chemical Name
5, 12-Naphthacenedione, 7, 8, 9, 10-tetrahydro-6, 8, 11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[(1S, 3R, 4aS, 9S, 9aR, 10aS)-octahydro-9-methoxy-1-methyl-1H-pyrano[4', 3':4, 5]oxazolo[2, 3-c][1, 4]oxazin-3-yl]oxy]-, (8S, 10S)
SMILES
O=C(C1=C(C2=C(C(O)=C1C3)C[C@@](O)(C(CO)=O)C[C@@H]2O[C@@H]4O[C@H]([C@H]5O[C@@H]6[C@@H](OC)OCCN6[C@H]5C4)C)O)C7=C3C=CC=C7OC
Molecular Formula
C32H35NO13
CAS Number
202350-68-3

Product References and Citations for PNU-159682 biochemical

1. Quintieri L, et al. Clin Cancer Res. 2005 Feb 15; 11 (4):1608-17.
2. Yu SF, et al. Clin Cancer Res. 2015 Jul 15; 21 (14):3298-306.
3. Mazzini S, et al. Bioorg Med Chem. 2012 Dec 15; 20 (24):6979-88.

Other Notes

Small volumes of PNU-159682 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PNU-159682 purchase

MBS3603151 is a biochemical targeting PNU-159682.
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