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TP455

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603178

TP455 (TP-455) is a highly potent, selective A2A adenosine receptor inverse agonist with IC50 of 1.9 nM in cyclic AMP assays in hA2A CHO cells. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TP455, Biochemical
Full Product Name
TP455
Product Synonym Names
TP-455; TP 455
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
353.4
Target
Adenosine Receptor
Receptor
Adenosine Receptor
Chemical Name
2-(2-furanyl)-N5-(2-methoxybenzyl)[1, 3]thiazolo[5, 4-d]pyrimidine-5, 7-diammine
SMILES
COC1=CC=CC=C1CNC2=NC(=C3C(=N2)SC(=N3)C4=CC=CO4)N
Molecular Formula
C17H15N5O2S
CAS Number
2042563-95-9

Product Categories/Family for TP455 biochemical

Apoptosis

Structure of TP455 biochemical

TP455 Biochemical – Cat# MBS3603178

Product References and Citations for TP455 biochemical

1. Gessi S, et al. Front Pharmacol. 2017 Dec 1; 8:888. doi: 10.3389/fphar.2017.00888.
2. Varano F, et al. J Med Chem. 2016 Dec 8; 59 (23):10564-10576.

Other Notes

Small volumes of TP455 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TP455 purchase

MBS3603178 is a biochemical targeting TP455.
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