RWJ 67657

Name: RWJ 67657; MyBioSource
Brand: MyBioSource
SKU: MBS3603438
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603438

A potent, selective, orally active p38 MAPK inhibitor that inhibits the production of TNF-alpha and IL-1beta by LPS-stimulated human PBMCs with IC50 of 3 and 11 nM, respectively. More details

$220 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RWJ 67657, Biochemical

Full Product Name

RWJ 67657

Product Synonym Names

RWJ67657; RWJ-67657

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

425.5

Target

p38 MAPK

Receptor

p38 MAPK

Chemical Name

4-[4-(4-fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol -2-yl]-3-butyn-1-ol

SMILES

FC(C=C1)=CC=C1C2=C(C3=CC=NC=C3)N(CCCC4=CC=CC=C4)C(C#CCCO)=N2

Molecular Formula

C27H24FN3O

CAS Number

215303-72-3

Product Categories/Family for RWJ 67657 biochemical

MAPK/ERK Signaling

Product References and Citations for RWJ 67657 biochemical

1. Wadsworth SA, et al. J Pharmacol Exp Ther. 1999 Nov; 291 (2):680-7.
2. Schafer PH, et al. J Immunol. 1999 Jun 15; 162 (12):7110-9.
3. Fijen JW, et al. Clin Exp Immunol. 2001 Apr; 124 (1):16-20.
4. Faas MM, et al. Clin Exp Immunol. 2002 Feb; 127 (2):337-43.

Other Notes

Small volumes of RWJ 67657 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS3603438 is a biochemical targeting RWJ 67657.

RWJ 67657

Product Overview

Product Categories/Family for RWJ 67657 biochemical

Structure of RWJ 67657 biochemical

Related Product Information for RWJ 67657 biochemical

Product References and Citations for RWJ 67657 biochemical

Other Notes

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