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SB-431542

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603942

SB-431542 is a potent, specific TGF-beta type I receptor (ALK5) inhibitor with IC50 of 94 nM. More details

$235 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SB-431542, Biochemical
Full Product Name
SB-431542
Product Synonym Names
SB 431542; SB431542
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
384.3875
Suitability
DMSO: >=40mg/mL
Ethanol: 11.17mg/mL (Need ultrasonic and warming)
Target
TGFBR
Receptor
ALK5; ALK4
Chemical Name
Benzamide, 4-[4-(1, 3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]
SMILES
O=C(N)C1=CC=C(C2=NC(C3=CC=C(OCO4)C4=C3)=C(C5=NC=CC=C5)N2)C=C1
Molecular Formula
C22H16N4O3
CAS Number
301836-41-9

Product Categories/Family for SB-431542 biochemical

Product References and Citations for SB-431542 biochemical

1. Callahan JF, et al. J Med Chem. 2002 Feb 28; 45 (5):999-1001.
2. Inman GJ, et al. Mol Pharmacol. 2002 Jul; 62 (1):65-74.
3. Matsuyama S, et al. Cancer Res. 2003 Nov 15; 63 (22):7791-8.
4. Hjelmeland MD, et al. Mol Cancer Ther. 2004 Jun; 3 (6):737-45.

Other Notes

Small volumes of SB-431542 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SB-431542 purchase

MBS3603942 is a biochemical targeting SB-431542.
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