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SCIO-469 (Talmapimod)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3603990

MBS3603990 is a biochemical targeting SCIO-469. A potent, selective p38alpha MAPK inhibitor with IC50 of 9 nM. More details

$250 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SCIO-469, Biochemical
Full Product Name
SCIO-469
Product Synonym Names
Talmapimod; SCIO469; SCIO 469
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
513.0035
Suitability
10mM in DMSO
Target
p38 MAPK
Receptor
p38 MAPK
Chemical Name
1H-Indole-3-acetamide, 6-chloro-5-[[(2R, 5S)-4-[(4-fluorophenyl)methyl]-2, 5-dimethyl-1-piperazinyl]carbonyl]-N, N, 1-trimethyl-alpha-oxo
SMILES
CC1CN(C(CN1C(=O)C2=C(C=C3C(=C2)C(=CN3C)C(=O)C(=O)N(C)C)Cl)C)CC4=CC=C(C=C4)F
Molecular Formula
C27H30ClFN4O3
CAS Number
309913-83-5

Product Categories/Family for SCIO-469 biochemical

Rheumatoid Arthritis; MAPK/ERK Signaling; Inflammation/Immunology

Structure of SCIO-469 biochemical

SCIO-469 Talmapimod Biochemical – Cat# MBS3603990

Product References and Citations for SCIO-469 biochemical

1. Navas TA, et al. Leukemia. 2006 Jun; 20 (6):1017-27.
2. Navas TA, et al. Blood. 2006 Dec 15; 108 (13):4170-7.
3. Hideshima T, et al. Oncogene. 2004 Nov 18; 23 (54):8766-76.

Other Notes

Small volumes of SCIO-469 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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