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SB-590885

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604394

MBS3604394 is a biochemical targeting SB-590885. A potent and selective B-Raf inhibitor with Kd of 0.3 nM. More details

$260 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SB-590885, Biochemical
Full Product Name
SB-590885
Product Synonym Names
SB590885; SB 590885
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
453.5356
Suitability
10mM in DMSO
Target
Raf
Receptor
B-Raf
Chemical Name
1H-Inden-1-one, 5-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-(4-pyridinyl)-1H-imidazol-4-yl]-2, 3-dihydro-, oxime
SMILES
CN(C)CCOC1=CC=C(C=C1)C2=N/C(=C/3C=CC4=C(CCC4=C3)N=O)/C(=C5C=CNC=C5)N2
Molecular Formula
C27H27N5O2
CAS Number
405554-55-4

Product Categories/Family for SB-590885 biochemical

MAPK/ERK Signaling; Cancer

Structure of SB-590885 biochemical

Sb-590885 Biochemical – Cat# MBS3604394

Product References and Citations for SB-590885 biochemical

1. Takle AK, et al. Bioorg Med Chem Lett. 2006 Jan 15; 16 (2):378-81.
2. King AJ, et al. Cancer Res. 2006 Dec 1; 66 (23):11100-5.
3. Villanueva J, et al. Cancer Cell. 2010 Dec 14; 18 (6):683-95.

Other Notes

Small volumes of SB-590885 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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