Pexacerfont (BMS-562086)

Name: Pexacerfont (BMS-562086); MyBioSource
Brand: MyBioSource
SKU: MBS3604547
Price: 260 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604547

A potent, selective and orally active CRF1 receptor antagonist with IC50 of 6.1 nM, >1,000-fold selectivity over CRF-binding protein and biogenic amine receptors. More details

$260 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Pexacerfont, Biochemical

Full Product Name

Pexacerfont

Product Synonym Names

BMS-562086; BMS562086; DPC-A69448

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

340.431

Target

CRF Receptor

Receptor

CRF Receptor

Chemical Name

8-(6-Methoxy-2-methyl-3-pyridinyl)-2, 7-dimethyl-N-[(1R)-1-methylpropyl]pyrazolo[1, 5-a]-1, 3, 5-triazin-4-amine

SMILES

CC[C@H](NC1=NC(C)=NC2=C(C3=CC=C(OC)N=C3C)C(C)=NN21)C

Molecular Formula

C18H24N6O

CAS Number

459856-18-9

Product Categories/Family for Pexacerfont biochemical

Irritable Bowel Syndrome; GPCR/G Protein; Other Indications

Product References and Citations for Pexacerfont biochemical

1. Kwako LE, et al. Neuropsychopharmacology. 2015 Mar 13; 40 (5):1053-63.
2. Gilligan PJ, et al. J Med Chem. 2009 May 14; 52 (9):3084-92.
3. Schwandt ML, et al. Neuropsychopharmacology. 2016 Nov; 41 (12):2818-2829.
4. Zhou L, et al. Drug Metab Dispos. 2012 Jun; 40 (6):1093-103.

Other Notes

Small volumes of Pexacerfont biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Pexacerfont purchase

MBS3604547 is a biochemical targeting Pexacerfont.