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Darunavir Ethanolate (TMC-114)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605406

A potent, selective HIV-1 protease inhibitor that is extremely potent against laboratory HIV-1 strains and primary clinical isolates with IC50 of 3 nM, IC90 of 9 nM. More details

$215 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Darunavir ethanolate, Biochemical
Full Product Name
Darunavir ethanolate
Product Synonym Names
TMC-114; UIC-94017
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
593.732
Suitability
10mM in DMSO
Target
HIV
Receptor
WTHIV-1protease
Chemical Name
Carbamic acid, N-[(1S, 2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3R, 3aS, 6aR)-hexahydrofuro[2, 3-b]furan-3-yl ester, compd. with ethanol(1:1)
SMILES
CCO.CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CO[C@@H]3[C@H]2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N
Molecular Formula
C29H43N3O8S
CAS Number
635728-49-3

Product References and Citations for Darunavir ethanolate biochemical

1. Surleraux DL, et al. J Med Chem. 2005 Mar 24; 48 (6):1813-22.
2. Koh Y, et al. Antimicrob Agents Chemother. 2003 Oct; 47 (10):3123-9.
3. KingnM, et al. J Virol. 2004 Nov; 78 (21):12012-21.

Other Notes

Small volumes of Darunavir ethanolate biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Darunavir ethanolate purchase

MBS3605406 is a biochemical targeting Darunavir ethanolate.
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