Ronacaleret (SB-751689)

Name: Ronacaleret (SB-751689); MyBioSource
Brand: MyBioSource
SKU: MBS3605863
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605863

A potent calcium sensing receptor (CaSR) negative allosteric modulator with IC50 of 146 nM for hCaSR. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Ronacaleret, Biochemical

Full Product Name

Ronacaleret

Product Synonym Names

SB-751689; SB751689

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

447.523

Target

CaSR

Receptor

CaSR

Chemical Name

3-[3-[(2R)-3-[[1-(2, 3-dihydro-1H-inden-2-yl)-2-methylpropan-2-yl]amino]-2-hydroxypropoxy]-4, 5-difluorophenyl]propanoic acid

SMILES

CC(C)(CC1CC2=CC=CC=C2C1)NCC(COC3=C(C(=CC(=C3)CCC(=O)O)F)F)O

Molecular Formula

C25H31F2NO4

CAS Number

753449-67-1

Product Categories/Family for Ronacaleret biochemical

Osteoporosis; GPCR/G Protein; Metabolic Disease

Product References and Citations for Ronacaleret biochemical

1. Balan G, et al. Bioorg Med Chem Lett. 2009 Jun 15; 19 (12):3328-32.
2. Fitzpatrick LA, et al. J Clin Endocrinol Metab. 2011 Aug; 96 (8):2441-9.
3. Fitzpatrick LA, et al. Bone. 2011 Oct; 49 (4):845-52.
4. Caltabiano S, et al. Bone. 2013 Sep; 56 (1):154-62.

Other Notes

Small volumes of Ronacaleret biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ronacaleret purchase

MBS3605863 is a biochemical targeting Ronacaleret.