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Dinaciclib (SCH 727965)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605940

A potent and selective CDK inhibitor with IC50 of 1, 1, 3 and 4 nM against CDK2, CDK5, CDK1 and CDK9, respectively. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Dinaciclib, Biochemical
Full Product Name
Dinaciclib
Product Synonym Names
SCH 727965; SCH727965; SCH-727965
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
396.486
Suitability
DMSO: >=56mg/mL
Target
CDK
Receptor
CDK1; CDK2; CDK5; CDK9
Chemical Name
2-Piperidineethanol, 1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1, 5-a]pyrimidin-5-yl]-, (2S)
SMILES
OCC[C@H]1N(C2=NC3=C(CC)C=NN3C(NCC4=C[N+]([O-])=CC=C4)=C2)CCCC1
Molecular Formula
C21H28N6O2
CAS Number
779353-01-4

Product References and Citations for Dinaciclib biochemical

1. Parry D, et al. Mol Cancer Ther. 2010 Aug; 9 (8):2344-53.
2. Paruch K, et al. ACS Med Chem Lett. 2010 May 17; 1 (5):204-8.
3. Feldmann G, et al. Cancer Biol Ther. 2011 Oct 1; 12 (7):598-609.
4. Johnson AJ, et al. Leukemia. 2012 Dec; 26 (12):2554-7.

Other Notes

Small volumes of Dinaciclib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Dinaciclib purchase

MBS3605940 is a biochemical targeting Dinaciclib.
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