Mk-0974 (Telcagepant)

Name: Mk-0974 (Telcagepant); MyBioSource
Brand: MyBioSource
SKU: MBS3605945
Price: 900 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3605945

A potent, selective, orally bioavailable CGRP receptor antagonist with Ki of 0.77 nM. More details

$900 / 50 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MK-0974, Biochemical

Full Product Name

MK-0974

Product Synonym Names

Telcagepant

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

566.523

Suitability

10mM in DMSO

Target

CGRP Receptor

Receptor

CGRP Receptor

Chemical Name

1-Piperidinecarboxamide, N-[(3R, 6S)-6-(2, 3-difluorophenyl)hexahydro-2-oxo-1-(2, 2, 2-trifluoroethyl)-1H-azepin-3-yl]-4-(2, 3-dihydro-2-oxo-1H-imidazo[4, 5-b]pyridin-1-yl)

SMILES

O=C(N1CCC(N(C2=CC=CN=C2N3)C3=O)CC1)N[C@H]4C(N(CC(F)(F)F)C[C@H](C5=CC=CC(F)=C5F)CC4)=O

Molecular Formula

C26H27F5N6O3

CAS Number

781649-09-0

Product Categories/Family for MK-0974 biochemical

Migraine; GPCR/G Protein; Neurological Disease

Product References and Citations for MK-0974 biochemical

1. Paone DV, et al. J Med Chem. 2007 Nov 15; 50 (23):5564-7.
2. Salvatore CA, et al. J Pharmacol Exp Ther. 2008 Feb; 324 (2):416-21.
3. Sinclair SR, et al. Br J Clin Pharmacol. 2010 Jan; 69 (1):15-22.

Other Notes

Small volumes of MK-0974 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MK-0974 purchase

MBS3605945 is a biochemical targeting MK-0974.