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SMER-18

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606756

A small molecule autophagy enhancer that induces autophagy independently of rapamycin in mammalian cells and enhances the clearance of autophagy substrates such as mutant huntingtin and A53T alpha-synuclein; reduces toxicity in Huntington's disease models. More details

$435 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SMER-18, Biochemical
Full Product Name
SMER-18
Product Synonym Names
SMER18
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
287.7409
Suitability
10mM in DMSO
Target
Autophagy
Receptor
Autophagy
Chemical Name
2-Buten-1-one, 1-(4-chlorophenyl)-3-[(3-hydroxyphenyl)amino]-, (2Z)
SMILES
OC1=C2N=C(C)C=CC2=CC=C1C(NC3=NC=CC(C)=C3)C4=CC=CC=C4[N+]([O-])=O
Molecular Formula
C16H14ClNO2
CAS Number
944153-47-3

Product Categories/Family for SMER-18 biochemical

Autophagy; Neurological Disease

Structure of SMER-18 biochemical

SMER-18 Biochemical – Cat# MBS3606756

Product References and Citations for SMER-18 biochemical

1. Sarkar S, et al. Nat Chem Biol. 2007 Jun; 3 (6):331-8.

Other Notes

Small volumes of SMER-18 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SMER-18 purchase

MBS3606756 is a biochemical targeting SMER-18.
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