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T-025

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606929

T-025 (T025, CLK inhibitor T-025) is an orally available, potent inhibitor of Cdc2-like kinases (CLKs) with Kd of 4.8, 0.096, 6.5, and 0.61 nM for CLK1, CLK2, CLK3, and CLK4, also inhibits DYRK1A and DYRK1B with IC50 of 0.074 and 1.5 nM. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
T-025, Biochemical
Full Product Name
T-025
Product Synonym Names
T025; CLK inhibitor T-025
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
382.431
Target
CLK
Receptor
CLK
Chemical Name
N2-methyl-N4-(pyrimidin-2-ylmethyl)-5-(quinolin-6-yl)-7H-pyrrolo[2, 3-d]pyrimidine-2, 4-diamine
Molecular Formula
C21H18N8

Product Categories/Family for T-025 biochemical

Cell Cycle/DNA Damage

Structure of T-025 biochemical

T-025 Biochemical – Cat# MBS3606929

Product References and Citations for T-025 biochemical

1. Iwai K, et al. EMBO Mol Med. 2018 May 16. pii: e8289.

Other Notes

Small volumes of T-025 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for T-025 purchase

MBS3606929 is a biochemical targeting T-025.
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