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SPI 112

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3607121

SPI-112, the SPI-112 methyl ester analog, can inhibit cellular Shp2 PTP activity. SPI-112 bound to Shp2 by surface plasmon resonance (SPR) and displayed competitive inhibitor kinetics to Shp2. More details

$235 / 10 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SPI 112, Biochemical
Full Product Name
SPI 112
Product Synonym Names
SPI-112; SPI112; SPI 112
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
468.45
Target
MTH1
Receptor
SHP-2
Chemical Name
(Z)-3-(2-(5-(N-(4-Fluorobenzyl)sulfamoyl)-2-oxoindolin-3-ylidene)hydrazinyl)benzoic acid
SMILES
O=C(O)c1cccc(N/N=C/2C(=O)Nc3c2cc(S(=O)(=O)NCc2ccc(F)cc2)cc3)c1
Molecular Formula
C22H17FN4O5S
CAS Number
1051387-90-6

Product Categories/Family for SPI 112 biochemical

Others

Structure of SPI 112 biochemical

SPI 112 Biochemical – Cat# MBS3607121

Product References and Citations for SPI 112 biochemical

1.Chen L, et al. Biochem Pharmacol. Inhibition of cellular Shp2 activity by a methyl ester analog of SPI-112. 2010 Sep 15; 80 (6):801-10

Other Notes

Small volumes of SPI 112 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SPI 112 purchase

MBS3607121 is a biochemical targeting SPI 112.
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