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Placenta Growth Factor (PLGF) ELISA Kit for Canine

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS038374

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used to determine the level of PLGF (hereafter termed "analyte") in undiluted original Canine serum, plasma or tissue homogenates… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Placenta Growth Factor (PLGF), ELISA Kit
Full Product Name
Canine Placenta Growth Factor ELISA Kit
Product Gene Name
PLGF elisa kit
Species Reactivity
Canine
Assay Type
Quantitative Sandwich
Samples
Undiluted original Canine serum, plasma or tissue homogenates samples
Detection Range
6.25pg/ml-200pg/ml
Sensitivity
1.0pg/ml
Specificity
No significant cross-reactivity or interference between this analyte and analogues is observed.
Preparation and Storage
Store all reagents at 2-8 degree C
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
Intra-assay Precision
Intra-assay CV (%) is less than 15%.
Molecular Weight
24,789 Da
Chromosome Location
Chromosome: 14; NC_000014.8 (75408533..75422467, complement). Location: 14q24.3
OMIM
601121
3D Structure
ModBase 3D Structure for P49763

Other Notes

Small volumes of PLGF elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLGF purchase

MBS038374 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Placenta Growth Factor (PLGF) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PLGF. The ELISA analytical biochemical technique of the MBS038374 kit is based on PLGF antibody-PLGF antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PLGF antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PLGF. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for PLGF. It may not necessarily be applicable to this product.

NCBI GI #
333033785
NCBI GeneID
5228
NCBI Accession #
NP_001193941.1
UniProt Primary Accession #
P49763
UniProt Secondary Accession #
Q07101; Q9BV78; Q9Y6S8
UniProt Related Accession #
P49763
GenBank Nucleotide #
NM_001207012.1
NCBI Official Full Name
placenta growth factor isoform 2
NCBI Official Synonym Full Names
placental growth factor
NCBI Official Symbol
PGF
NCBI Official Synonym Symbols
PGFL; PLGF; PlGF-2; D12S1900; SHGC-10760
UniProt Protein Name
Placenta growth factor
Protein Family
Placenta growth factor
UniProt Gene Name
PGF
UniProt Synonym Gene Names
PGFL; PLGF; PlGF
UniProt Entry Name
PLGF_HUMAN
NCBI Protein Information
placenta growth factor; placental growth factor, vascular endothelial growth factor-related protein

NCBI Summary for PLGF

This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]

UniProt Comments for PLGF

PGF: Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. Belongs to the PDGF/VEGF growth factor family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: extracellular space; membrane; extracellular region

Molecular Function: heparin binding; protein binding; protein homodimerization activity; growth factor activity; protein heterodimerization activity

Biological Process: response to drug; organ regeneration; female pregnancy; signal transduction; cellular response to hormone stimulus; positive regulation of angiogenesis; cell-cell signaling; ureteric bud branching; positive regulation of cell division; positive regulation of cell proliferation; response to hypoxia; positive regulation of endothelial cell proliferation; sprouting angiogenesis; cell differentiation; vascular endothelial growth factor receptor signaling pathway
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Research Articles on PLGF

1. Placental growth factor has a role in adverse outcomes in patients with suspected preeclampsia or intrauterine growth restriction

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PLGF elisa kit

 Reference Product  PubMed Publications
 VEGFA elisa kit  >20 publications with PLGF and VEGFA
 FLT1 elisa kit  >15 publications with PLGF and FLT1
 IL6 elisa kit  >12 publications with PLGF and IL6
 KDR elisa kit  >8 publications with PLGF and KDR
 FLT4 elisa kit  >2 publications with PLGF and FLT4
 AKT1 elisa kit  >1 publications with PLGF and AKT1
 PIK3CA elisa kit  >1 publications with PLGF and PIK3CA
 NRP1 elisa kit  >1 publications with PLGF and NRP1

Pathways associated with PLGF elisa kit

 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By VEGF Pathway antibodies  Signaling By VEGF Pathway Diagram
 VEGF Binds To VEGFR Leading To Receptor Dimerization Pathway antibodies  VEGF Binds To VEGFR Leading To Receptor Dimerization Pathway Diagram
 VEGF Ligand-receptor Interactions Pathway antibodies  VEGF Ligand-receptor Interactions Pathway Diagram

Diseases associated with PLGF elisa kit

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >369 publications with PLGF and Cardiovascular Diseases
 Inflammation Antibodies  >274 publications with PLGF and Inflammation
 Hypertension Antibodies  >191 publications with PLGF and Hypertension
 Disease Models, Animal Antibodies  >155 publications with PLGF and Disease Models, Animal
 Neoplasms Antibodies  >150 publications with PLGF and Neoplasms
 Necrosis Antibodies  >148 publications with PLGF and Necrosis
 Heart Diseases Antibodies  >123 publications with PLGF and Heart Diseases
 Atherosclerosis Antibodies  >89 publications with PLGF and Atherosclerosis
 Drug Toxicity Antibodies  >80 publications with PLGF and Drug Toxicity
 Brain Diseases Antibodies  >69 publications with PLGF and Brain Diseases

Organs/Tissues associated with PLGF elisa kit

 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >749 publications with PLGF and Ovary
 Uterus Antibodies  >720 publications with PLGF and Uterus
 Muscle Antibodies  >497 publications with PLGF and Muscle
 Heart Antibodies  >241 publications with PLGF and Heart
 Lung Antibodies  >233 publications with PLGF and Lung
 Kidney Antibodies  >210 publications with PLGF and Kidney
 Placenta Antibodies  >199 publications with PLGF and Placenta
 Embryonic Tissue Antibodies  >195 publications with PLGF and Embryonic Tissue
 Brain Antibodies  >194 publications with PLGF and Brain
 Liver Antibodies  >133 publications with PLGF and Liver
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