Rabbit Anti-APBA3 Polyclonal Antibody – Cat# MBS3905745

Detection of human APBA3 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-APBA3 antibody (MBS3905745 lot 1) used for IP at 6 ug per reaction. APBA3 was also immunoprecipitated by rabbit anti-APBA3 antibody BL22231. For blotting immunoprecipitated APBA3, MBS3905745 was used at 0.4 mg/ml. Detection: Chemiluminescence with an exposure time of 75 seconds.

APBA3 Antibody – Rabbit Polyclonal

Name: APBA3 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS3905745
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3905745

Amyloid beta A4 precursor protein-binding family A member 3 (APBA3) may modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. APBA3 may enhance the activity of HIF1A in macrophages by inhibiting the activity of… More details

$250 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

APBA3, Polyclonal Antibody

Full Product Name

Rabbit anti-APBA3 Antibody, Affinity Purified

Product Gene Name

anti-APBA3 antibody

Product Synonym Names

neuronal munc18-1-interacting protein 3; amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2); X11-like 2 protein; X11L2; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein; neuron-specific X11L2 protein; mint-3; mint3; amyloid-beta A4 precursor protein-binding family A member 3; adapter protein X11gamma; MGC:15815; Amyloid beta A4 precursor protein-binding family A member 3; amyloid beta precursor protein binding family A member 3

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Purity/Purification

Antigen Affinity Purified

Concentration

1000ug/ml (lot specific)

Preparation and Storage

Store at 2-8 degree C
Shelf Life: 1 year from date of receipt

Molecular Weight

61,454 Da

Chromosome Location

Chromosome: 19; NC_000019.9 (3750771..3761673, complement). Location: 19p13.3

OMIM

604262

3D Structure

ModBase 3D Structure for O96018

Immunogen

Between 1 and 50

Conjugation

Unconjugated

Product Categories/Family for anti-APBA3 antibody

Primary Antibodies

Applications Tested/Suitable for anti-APBA3 antibody

Immunoprecipitation (IP)

Application Notes for anti-APBA3 antibody

IP: 6ug/mg lysate

Other Notes

Small volumes of anti-APBA3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for APBA3 purchase

MBS3905745 is an antibody targeting APBA3. Also known as Rabbit anti-APBA3 Antibody, Affinity Purified. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for APBA3. It may not necessarily be applicable to this product.

NCBI GI #

11342678

NCBI GeneID

9546

NCBI Accession #

NP_004877.1

UniProt Primary Accession #

O96018

UniProt Secondary Accession #

O60483; Q9UPZ2

UniProt Related Accession #

O96018

GenBank Nucleotide #

NM_004886.3

NCBI Official Full Name

amyloid beta A4 protein-binding family A member 3

NCBI Official Synonym Full Names

amyloid beta (A4) precursor protein-binding, family A, member 3

NCBI Official Symbol

APBA3

NCBI Official Synonym Symbols

X11L2; mint3; MGC:15815

UniProt Protein Name

Amyloid beta A4 precursor protein-binding family A member 3

UniProt Synonym Protein Names

Adapter protein X11gamma; Neuron-specific X11L2 protein; Neuronal Munc18-1-interacting protein 3

Protein Family

Amyloid beta A4 precursor protein-binding family

UniProt Gene Name

APBA3

UniProt Synonym Gene Names

MINT3; X11L2; Mint-3

UniProt Entry Name

APBA3_HUMAN

NCBI Protein Information

amyloid beta A4 precursor protein-binding family A member 3; mint-3; X11-like 2 protein; adapter protein X11gamma; neuron-specific X11L2 protein; neuronal munc18-1-interacting protein 3; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein; a

NCBI Summary for APBA3

The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease. [provided by RefSeq, Jul 2008]

UniProt Comments for APBA3

APBA3: May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: perinuclear region of cytoplasm

Molecular Function: enzyme inhibitor activity; protein binding; enzyme binding; beta-amyloid binding

Biological Process: synaptic transmission; protein transport; regulation of gene expression; in utero embryonic development; negative regulation of catalytic activity

Research Articles on APBA3

1. These results indicate that all three amyloid beta protein precursor family members are capable of activating gene transcription via Mint3-Taz and Mint3-Yap.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-APBA3 antibody

Reference Product	PubMed Publications
APP antibody	>8 publications with APBA3 and APP
BCR antibody	>1 publications with APBA3 and BCR

Diseases associated with anti-APBA3 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>5 publications with APBA3 and Neoplasms
Brain Diseases Antibodies	>4 publications with APBA3 and Brain Diseases
Inflammation Antibodies	>2 publications with APBA3 and Inflammation
Drug Toxicity Antibodies	>1 publications with APBA3 and Drug Toxicity
Precancerous Conditions Antibodies	>1 publications with APBA3 and Precancerous Conditions
Hyperplasia Antibodies	>1 publications with APBA3 and Hyperplasia

Organs/Tissues associated with anti-APBA3 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>7 publications with APBA3 and Brain
Intestine Antibodies	>1 publications with APBA3 and Intestine
Blood Antibodies	>1 publications with APBA3 and Blood
Testis Antibodies	>1 publications with APBA3 and Testis
Kidney Antibodies	>1 publications with APBA3 and Kidney
Placenta Antibodies	>1 publications with APBA3 and Placenta