Mouse Anti-PLAP Monoclonal Antibody – Cat# MBS395047

Placental Alakaline Phosphatase (PLAP) Antibody – Mouse Monoclonal

Name: PLAP Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS395047
Price: 425 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS395047

Placental alkaline phosphatase is a throphoblast-derived antigen from human placenta. It is a membrane-associated antigen present in high frequency in gynacological cancers and in lower frequency in other tumors. This antibody can be used as an… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Placental Alakaline Phosphatase (PLAP), Monoclonal Antibody

Full Product Name

Placental Alakaline Phosphatase (PLAP)

Product Gene Name

anti-PLAP antibody

Clonality

Monoclonal

Isotype

IgG2a

Clone Number

H7E8

Host

Mouse

Species Reactivity

Human

Form/Format

Provided as solution in phosphate buffered saline with 0.08% sodium azide

Purity/Purification

Protein A/G Chromatography

Preparation and Storage

Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles

Molecular Weight

87,157 Da

Chromosome Location

Chromosome: 9; NC_000009.11 (26903368..26947468, complement). Location: 9p21

OMIM

603873

3D Structure

ModBase 3D Structure for Q9Y263

Immunogen

Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with purified placental alkaline phosphatase and mouse myeloma cells

Product Categories/Family for anti-PLAP antibody

Monoclonal Antibody; Protein Phosphatases

Applications Tested/Suitable for anti-PLAP antibody

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) Frozen

Other Notes

Small volumes of anti-PLAP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLAP purchase

MBS395047 is an antibody targeting PLAP. Also known as Placental Alakaline Phosphatase (PLAP). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PLAP. It may not necessarily be applicable to this product.

NCBI GI #

72534670

NCBI GeneID

9373

NCBI Accession #

NP_001026859.1

UniProt Primary Accession #

Q9Y263

UniProt Secondary Accession #

Q53EU5; Q5VY33; Q9NUL8; Q9NVE9; Q9UF53; Q9Y5L1

UniProt Related Accession #

Q9Y263

GenBank Nucleotide #

NM_001031689.2

NCBI Official Full Name

phospholipase A-2-activating protein

NCBI Official Synonym Full Names

phospholipase A2-activating protein

NCBI Official Symbol

PLAA

NCBI Official Synonym Symbols

DOA1; PLAP; PLA2P

UniProt Protein Name

Phospholipase A-2-activating protein

Protein Family

Low-affinity putrescine importer

UniProt Gene Name

PLAA

UniProt Synonym Gene Names

PLAP; PLA2P; PLAP

UniProt Entry Name

PLAP_HUMAN

NCBI Protein Information

phospholipase A-2-activating protein; DOA1 homolog; phospholipase A2 activating protein

UniProt Comments for PLAP

Function: Involved in the maintenance of ubiquitin levels

By similarity.

Subunit structure: Interacts with ubiquitin. Interacts with VCP. Ref.11

Domain: The PUL domain is composed of 6 armadillo-like repeats and mediates the interaction with VCP C-terminus. Ref.12The PFU domain mediates interaction with ubiquitin. Ref.12

Sequence similarities: Belongs to the WD repeat PLAP family.Contains 6 ARM repeats.Contains 1 PFU domain.Contains 1 PUL domain.Contains 7 WD repeats.

Sequence caution: The sequence AAD03030.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAD42075.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAD42075.1 differs from that shown. Reason: Frameshift at position 698. The sequence BAA92105.1 differs from that shown. Reason: Erroneous termination at position 545. Translated as Gln.The sequence BAD97264.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence CAB42881.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence CAH72641.1 differs from that shown. Reason: Erroneous gene model prediction.

Research Articles on PLAP

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PLAP antibody

Reference Product	PubMed Publications
PDIA3 antibody	>3 publications with PLAP and PDIA3
VCP antibody	>2 publications with PLAP and VCP
CAV1 antibody	>1 publications with PLAP and CAV1

Pathways associated with anti-PLAP antibody

Products by Pathway	Pathway Diagram
Protein Processing In Endoplasmic Reticulum Pathway antibodies	Protein Processing In Endoplasmic Reticulum Pathway Diagram
Protein Processing In Endoplasmic Reticulum Pathway antibodies	Protein Processing In Endoplasmic Reticulum Pathway Diagram

Organs/Tissues associated with anti-PLAP antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>145 publications with PLAP and Liver
Blood Antibodies	>93 publications with PLAP and Blood
Kidney Antibodies	>20 publications with PLAP and Kidney
Lung Antibodies	>12 publications with PLAP and Lung
Brain Antibodies	>12 publications with PLAP and Brain
Vascular Antibodies	>8 publications with PLAP and Vascular
Muscle Antibodies	>4 publications with PLAP and Muscle
Adipose Tissue Antibodies	>4 publications with PLAP and Adipose Tissue
Bone Antibodies	>4 publications with PLAP and Bone
Connective Tissue Antibodies	>4 publications with PLAP and Connective Tissue