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Monocarboxylate Transport 2 (SLC16A7) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS396047

Functions as a proton-linked monocarboxylate transporter and catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone… More details

$500 / 0.1 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Monocarboxylate Transport 2 (SLC16A7), Polyclonal Antibody
Full Product Name
Monocarboxylate Transport 2
Product Gene Name
Product Synonym Names
MCT2; Solute carrier family 16 member 7; SLC16A7
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Purity/Purification
Ammonium Sulfate Precipitation
Preparation and Storage
Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Molecular Weight
52 kDa
Chromosome Location
Chromosome: 12; NC_000012.11 (59989821..60183636). Location: 12q13
OMIM
603654
3D Structure
ModBase 3D Structure for O60669
Immunogen
Synthetic peptide derived from human MCT2 protein
Positive Control
Testis, spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocyte.

Product Categories/Family for anti-SLC16A7 antibody

Applications Tested/Suitable for anti-SLC16A7 antibody
Western Blot (WB)

Other Notes

Small volumes of anti-SLC16A7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC16A7 purchase

MBS396047 is an antibody targeting SLC16A7. Also known as Monocarboxylate Transport 2. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC16A7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
monocarboxylate transporter 2
NCBI Official Synonym Full Names
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
NCBI Official Symbol
SLC16A7
NCBI Official Synonym Symbols
MCT2
UniProt Protein Name
Monocarboxylate transporter 2
UniProt Synonym Protein Names
Solute carrier family 16 member 7
UniProt Gene Name
SLC16A7
UniProt Synonym Gene Names
MCT2; MCT 2
UniProt Entry Name
MOT2_HUMAN
NCBI Protein Information
monocarboxylate transporter 2

NCBI Summary for SLC16A7

This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
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UniProt Comments for SLC16A7

Function: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a high affinity pyruvate transporter.

Subunit structure: Interacts with GRID2IP

By similarity.

Subcellular location: Cell membrane; Multi-pass membrane protein.

Tissue specificity: High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and Leukocyte. Restricted expression in normal tissues, but widely expressed in cancer cells.

Sequence similarities: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. [View classification]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC16A7 antibody

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