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PLA2G12B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS415442

Phospholipase A2 (PLA2) enzymes catalyze hydrolysis of glycolipids to release free fatty acids and lysophospholipids. PLA2G12B belongs to the PLA2 family, but it is catalytically inactive due to an amino acid change in its active site and has altered… More details

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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
PLA2G12B, Polyclonal Antibody
Full Product Name
Anti-PLA2G12B Antibody
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
Purified
Concentration
100ug/100ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
21,588 Da
OMIM
611653
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
a 15 amino acid peptide from near the N terminal residues of human PLA2G12B protein.
Applications Tested/Suitable for anti-PLA2G12B antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-PLA2G12B antibody
Peptide ELISA titer: 1:80,000
Western blot analysis: 1:200-500
Optimal dilutions/concentrations should be determined by the end user.

Western Blot (WB) of anti-PLA2G12B antibody

Rabbit Anti-PLA2G12B Polyclonal Antibody – Cat# MBS415442

Product References and Citations for anti-PLA2G12B antibody

(1) Rouault,M., Bollinger,J.G., Lazdunski,M et,al Novel mammalian group XII secreted phospholipase A2 lacking enzymatic activity
Biochemistry.2003;42 (39):11494-11503.

Other Notes

Small volumes of anti-PLA2G12B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLA2G12B purchase

MBS415442 is an antibody targeting PLA2G12B. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PLA2G12B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Homo sapiens phospholipase A2, group XIIB (PLA2G12B), mRNA
NCBI Official Synonym Full Names
phospholipase A2, group XIIB
NCBI Official Symbol
PLA2G12B
NCBI Official Synonym Symbols
GXIIB; FKSG71; PLA2G13; GXIIIsPLA2
UniProt Protein Name
Group XIIB secretory phospholipase A2-like protein
UniProt Synonym Protein Names
Group XIII secretory phospholipase A2-like protein; GXIII sPLA2-like; sPLA2-GXIIB; GXIIB
UniProt Gene Name
PLA2G12B
UniProt Entry Name
PG12B_HUMAN
NCBI Protein Information
group XIIB secretory phospholipase A2-like protein; group XIII secreted phospholipase A2; group XIII secretory phospholipase A2-like protein; phospholipase A2, group XIII; sPLA2-GXIIB

NCBI Summary for PLA2G12B

Phospholipase A2 (PLA2) enzymes catalyze hydrolysis of glycolipids to release free fatty acids and lysophospholipids. PLA2G12B belongs to the PLA2 family, but it is catalytically inactive due to an amino acid change in its active site and has altered phospholipid-binding properties (Rouault et al., 2003 [PubMed 14516201]).[supplied by OMIM, Mar 2008]
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UniProt Comments for PLA2G12B

PLA2G12B: Not known; does not seem to have catalytic activity. Belongs to the phospholipase A2 family.

Protein type: Lipid Metabolism - alpha-linolenic acid; Secreted; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - ether lipid; Lipid Metabolism - linoleic acid; Secreted, signal peptide; Lipid Metabolism - arachidonic acid

Chromosomal Location of Human Ortholog: 10q22.1

Cellular Component: extracellular region

Molecular Function: phospholipase A2 activity; calcium ion binding

Biological Process: cholesterol homeostasis; lipid catabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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