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AFF3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS415462

This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
AFF3, Polyclonal Antibody
Full Product Name
Anti-AFF3 Antibody
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human. Not yet tested in other species
Form/Format
Liquid
Purity/Purification
Affinity purified
Concentration
100ug/100ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
136,352 Da
OMIM
601464
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Applications Tested/Suitable for anti-AFF3 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-AFF3 antibody
Peptide ELISA titer: 1:5,000-1:10,000
Western blot analysis: 1:1,000-1:2,000
Optimal dilutions/concentrations should be determined by the end user.

Western Blot (WB) of anti-AFF3 antibody

Rabbit Anti-AFF3 Polyclonal Antibody – Cat# MBS415462

Product References and Citations for anti-AFF3 antibody

(1) Plant,D., Thomson,W., Lunt,M., et al. The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register. Rheumatology (Oxford) 50 (1), 78-84 (2011)

Other Notes

Small volumes of anti-AFF3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AFF3 purchase

MBS415462 is an antibody targeting AFF3. Reactive in Human. Not yet tested in other species. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AFF3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
AF4/FMR2 family member 3 isoform 1
NCBI Official Synonym Full Names
AF4/FMR2 family, member 3
NCBI Official Symbol
AFF3
NCBI Official Synonym Symbols
LAF4; MLLT2-like
UniProt Protein Name
AF4/FMR2 family member 3
UniProt Synonym Protein Names
Lymphoid nuclear protein related to AF4; Protein LAF-4
Protein Family
UniProt Gene Name
AFF3
UniProt Entry Name
AFF3_HUMAN
NCBI Protein Information
AF4/FMR2 family member 3; MLLT2-related protein; lymphoid nuclear protein 4; lymphoid nuclear protein related to AF4; protein LAF-4

UniProt Comments for AFF3

AFF3: Putative transcription activator that may function in lymphoid development and oncogenesis. Binds, in vitro, to double- stranded DNA. Belongs to the AF4 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 2q11.2-q12

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: double-stranded DNA binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; embryonic hindlimb morphogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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