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IL20RB Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS415591

IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20 (IL20; MIM 605619) (Blumberg et al., 2001 [PubMed 11163236]).[supplied by OMIM, Feb 2009] More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
IL20RB, Polyclonal Antibody
Full Product Name
Anti-IL20RB Antibody
Product Gene Name
anti-IL20RB antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human. Predicted: Mouse, Rat.
Form/Format
Liquid
Purity/Purification
Affinity purified
Concentration
100ug/100ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
16,945 Da
OMIM
605621
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Rabbit polyclonal IL20RB (1) antibody was raised against a recombinate human IL20RB protein 30-231aa (BC063696).
Applications Tested/Suitable for anti-IL20RB antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-IL20RB antibody
ELISA titer: 1:20,000-1:80,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.

Testing Data of anti-IL20RB antibody

Rabbit Anti-IL20RB Polyclonal Antibody – Cat# MBS415591

Product References and Citations for anti-IL20RB antibody

(1) Zhu,H. and Yang,Z.B. Expression pattern of mda-7/IL-24 receptors in liver cancer cell lines. HBPD INT 8 (4), 402-406 (2009).

Other Notes

Small volumes of anti-IL20RB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL20RB purchase

MBS415591 is an antibody targeting IL20RB. Reactive in Human. Predicted: Mouse, Rat.. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IL20RB. It may not necessarily be applicable to this product.

NCBI GI #
40255073
NCBI GeneID
53833
NCBI Accession #
NP_653318.2
UniProt Secondary Accession #
Q6P438; Q8IYY5; Q8TAJ7; B4DL40
UniProt Related Accession #
Q6UXL0
GenBank Nucleotide #
NM_144717.3
NCBI Official Full Name
interleukin-20 receptor subunit beta
NCBI Official Synonym Full Names
interleukin 20 receptor beta
NCBI Official Symbol
IL20RB
NCBI Official Synonym Symbols
DIRS1; FNDC6; IL-20R2
UniProt Protein Name
Interleukin-20 receptor subunit beta
UniProt Synonym Protein Names
Fibronectin type III domain containing 6; FNDC6; IL-20R2
Protein Family
Interleukin-20 receptor
UniProt Gene Name
IL20RB
UniProt Entry Name
I20RB_HUMAN
NCBI Protein Information
interleukin-20 receptor subunit beta; IL-20 receptor subunit beta; IL-20R-beta; IL-20RB; fibronectin type III domain containing 6; interleukin-20 receptor II

UniProt Comments for IL20RB

IL20RB: The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24. Belongs to the type II cytokine receptor family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q22.3

Cellular Component: plasma membrane; integral to membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interleukin-20 binding

Biological Process: positive regulation of interleukin-4 production; inflammatory response to antigenic stimulus; negative regulation of T cell proliferation; homeostasis of number of cells within a tissue; immune response-inhibiting signal transduction; negative regulation of interferon-gamma production; cytokine and chemokine mediated signaling pathway; negative regulation of type IV hypersensitivity; positive regulation of interleukin-10 production; negative regulation of interleukin-2 production
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Research Articles on IL20RB

1. Trabecular meshwork cells express IL-20 receptors; Mutation of the T104 residue in IL-20R2 leads to a reduction in STAT3 phosphorylation as well as decreased matrix metalloproteinase activity

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IL20RB antibody

 Reference Product  PubMed Publications
 IL20 antibody  >3 publications with IL20RB and IL20
 IL20RA antibody  >2 publications with IL20RB and IL20RA

Pathways associated with anti-IL20RB antibody

 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram

Diseases associated with anti-IL20RB antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >2 publications with IL20RB and Inflammation

Organs/Tissues associated with anti-IL20RB antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >2 publications with IL20RB and Skin
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