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ARF4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS415855

This gene is a member of the human ARF gene family whose members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase… More details

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Product Overview

Product Name
ARF4, Polyclonal Antibody
Full Product Name
Anti-ARF4 Antibody
Product Gene Name
anti-ARF4 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human. Predicted: Mouse, Rat
Form/Format
Liquid
Purity/Purification
Affinity purified
Concentration
100ug/100ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
20,511 Da
OMIM
601177
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Rabbit polyclonal ARF4 (1) antibody was raised against a recombinated human ARF4 protein 2-180aa (BC003364).
Applications Tested/Suitable for anti-ARF4 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ARF4 antibody
ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:1,000-1:2,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.

Testing Data of anti-ARF4 antibody

Rabbit Anti-ARF4 Polyclonal Antibody – Cat# MBS415855

Product References and Citations for anti-ARF4 antibody

(1) Jang,S.Y., Jang,S.W., Ko,J. Regulation of ADP-ribosylation factor 4 expression by small leucine zipper protein and involvement in breast cancer cell migration. Cancer Lett. 314 (2), 185-197 (2012).

Other Notes

Small volumes of anti-ARF4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARF4 purchase

MBS415855 is an antibody targeting ARF4. Reactive in Human. Predicted: Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ARF4. It may not necessarily be applicable to this product.

NCBI GI #
13097191
NCBI GeneID
378
NCBI Accession #
BC003364
UniProt Secondary Accession #
P21371; B2R7J7
UniProt Related Accession #
P18085
NCBI Official Full Name
Homo sapiens ADP-ribosylation factor 4, mRNA
NCBI Official Synonym Full Names
ADP-ribosylation factor 4
NCBI Official Symbol
ARF4
NCBI Official Synonym Symbols
ARF2
UniProt Protein Name
ADP-ribosylation factor 4
Protein Family
ADP-ribosylation factor
UniProt Gene Name
ARF4
UniProt Entry Name
ARF4_HUMAN
NCBI Protein Information
ADP-ribosylation factor 4; ADP-ribosylation factor 2

UniProt Comments for ARF4

ARF4: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family.

Protein type: G protein, monomeric; G protein, monomeric, ARF; Motility/polarity/chemotaxis; G protein

Chromosomal Location of Human Ortholog: 3p14.3

Cellular Component: Golgi apparatus; membrane; cytosol

Molecular Function: GTPase activity; protein binding; GTP binding; epidermal growth factor receptor binding

Biological Process: epidermal growth factor receptor signaling pathway; vesicle-mediated transport; phospholipase D activation; protein amino acid ADP-ribosylation; protein transport; cell migration; organelle organization and biogenesis; small GTPase mediated signal transduction; positive regulation of transcription from RNA polymerase II promoter; brain development; response to axon injury; negative regulation of apoptosis
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Research Articles on ARF4

1. ARF1+ARF4 are required for integrity of recycling endosomes but are involved in distinct transport pathways: the pair regulates retrograde transport from endosomes to the TGN.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ARF4 antibody

 Reference Product  PubMed Publications
 ASAP1 antibody  >7 publications with ARF4 and ASAP1
 EGFR antibody  >3 publications with ARF4 and EGFR
 PKD1 antibody  >1 publications with ARF4 and PKD1

Pathways associated with anti-ARF4 antibody

 Products by Pathway  Pathway Diagram
 Assembly Of The Primary Cilium Pathway antibodies  Assembly Of The Primary Cilium Pathway Diagram
 Cargo Trafficking To The Periciliary Membrane Pathway antibodies  Cargo Trafficking To The Periciliary Membrane Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 ErbB1 Downstream Signaling Pathway antibodies  ErbB1 Downstream Signaling Pathway Diagram
 Organelle Biogenesis And Maintenance Pathway antibodies  Organelle Biogenesis And Maintenance Pathway Diagram
 VxPx Cargo-targeting To Cilium Pathway antibodies  VxPx Cargo-targeting To Cilium Pathway Diagram

Diseases associated with anti-ARF4 antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >2 publications with ARF4 and Kidney Diseases
 Inflammation Antibodies  >1 publications with ARF4 and Inflammation
 Weight Loss Antibodies  >1 publications with ARF4 and Weight Loss

Organs/Tissues associated with anti-ARF4 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with ARF4 and Brain
 Kidney Antibodies  >7 publications with ARF4 and Kidney
 Heart Antibodies  >6 publications with ARF4 and Heart
 Blood Antibodies  >4 publications with ARF4 and Blood
 Muscle Antibodies  >4 publications with ARF4 and Muscle
 Eye Antibodies  >4 publications with ARF4 and Eye
 Lung Antibodies  >4 publications with ARF4 and Lung
 Placenta Antibodies  >2 publications with ARF4 and Placenta
 Spleen Antibodies  >2 publications with ARF4 and Spleen
 Ear Antibodies  >2 publications with ARF4 and Ear
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