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AMICA1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS416860

MBS416860 is an antibody targeting AMICA1. Reactive in Human. Host: Rabbit. Rabbit polyclonal AMICA1 More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AMICA1, Polyclonal Antibody
Full Product Name
Anti-AMICA1 Antibody
Product Gene Name
anti-AMICA1 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Affinity purified
Concentration
100ug/100ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
40,136 Da
OMIM
609770
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Raised against a recombinate human AMICA1 protein 6-235aa (BC100797).
Applications Tested/Suitable for anti-AMICA1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-AMICA1 antibody
ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:500-1:1,000
Optimal dilutions/concentrations should be determined by the end user

Western Blot (WB) of anti-AMICA1 antibody

Rabbit Anti-AMICA1 Polyclonal Antibody – Cat# MBS416860

Product References and Citations for anti-AMICA1 antibody

(1) Rose,J.E., Behm,F.M., Drgon,T., et al. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.Mol. Med. 16 (7-8), 247-253 (2010).

Other Notes

Small volumes of anti-AMICA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AMICA1. It may not necessarily be applicable to this product.

NCBI GI #
71681554
NCBI GeneID
120425
NCBI Accession #
BC100797
UniProt Secondary Accession #
Q496M1; Q5DTC6; Q7Z499; Q8N9I7; Q8NF70; B0YIV1; B0YIV2
UniProt Related Accession #
Q86YT9
NCBI Official Full Name
Homo sapiens adhesion molecule, interacts with CXADR antigen 1, mRNA
NCBI Official Synonym Full Names
adhesion molecule, interacts with CXADR antigen 1
NCBI Official Symbol
AMICA1
NCBI Official Synonym Symbols
JAML; AMICA; Gm638; CREA7-1; CREA7-4
UniProt Protein Name
Junctional adhesion molecule-like
UniProt Synonym Protein Names
Adhesion molecule interacting with CXADR antigen 1; Dendritic cell-specific protein CREA7-1
UniProt Gene Name
AMICA1
UniProt Entry Name
JAML1_HUMAN
NCBI Protein Information
junctional adhesion molecule-like; adhesion molecule AMICA; adhesion molecule interacting with CXADR antigen 1; dendritic-cell specific protein CREA7-1; dendritic-cell specific protein CREA7-4

UniProt Comments for AMICA1

AMICA1: an adhesion molecule that may function in the migration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells. Up-regulated upon retinoic acid, Me2SO and PMA treatment in differentiating myeloid leukemia cells. Three alternatively spliced isoforms have been described.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: tight junction; plasma membrane; integral to membrane

Molecular Function: integrin binding; protein homodimerization activity; cell adhesion molecule binding

Biological Process: heterophilic cell adhesion; neutrophil chemotaxis; regulation of immune response; positive regulation of epithelial cell proliferation involved in wound healing; blood coagulation; gamma-delta T cell activation; leukocyte migration
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Research Articles on AMICA1

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-AMICA1 antibody

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies  Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram

Organs/Tissues associated with anti-AMICA1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4 publications with AMICA1 and Blood
 Bone Antibodies  >1 publications with AMICA1 and Bone
 Bone Marrow Antibodies  >1 publications with AMICA1 and Bone Marrow
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