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Estrogen Receptor-Beta (ESR2) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS418386

The estrogen receptor (ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Alternative splicing results in several ER mRNA transcripts, which differ primarily… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Estrogen Receptor-beta (ESR2), Monoclonal Antibody
Full Product Name
Anti-Estrogen Receptor-beta Antibody
Product Gene Name
anti-ESR2 antibody
Clonality
Monoclonal
Isotype
IgG1
Host
Mouse
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Purified by protein A affinity chromatography.
Concentration
1ug/ul (lot specific)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
59,032 Da
3D Structure
ModBase 3D Structure for Q9XSB5
Immunogen
Ni-NTA purified recombinant human ER-alpha (410-592aa) expressed in E Coli strain BL21 (DE3)
Storage Buffer
PBS, pH 7.4 with 0.05% sodium azide.
Applications Tested/Suitable for anti-ESR2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ESR2 antibody
Western Blot: 1: 100- 1: 500
IHC (P): 1: 100- 1: 500
IHC (F): 1: 100- 1: 500

Western Blot (WB) of anti-ESR2 antibody

Mouse Anti-ESR2 Monoclonal Antibody – Cat# MBS418386

Immunohistochemistry (IHC) of anti-ESR2 antibody

Mouse Anti-ESR2 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS418386

Product References and Citations for anti-ESR2 antibody

1. Paech K. Science 1997, 277: 1508- 10. 2. Pertschuk LP¯Å'Cancer, 1996. 199677: 514- 9.

Other Notes

Small volumes of anti-ESR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ESR2 purchase

MBS418386 is an antibody targeting ESR2. Also known as Anti-Estrogen Receptor-beta Antibody. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ESR2. It may not necessarily be applicable to this product.

NCBI GI #
164448731
NCBI GeneID
281146
NCBI Accession #
NP_776476.2
UniProt Primary Accession #
Q9XSB5
UniProt Secondary Accession #
Q9TTS2
UniProt Related Accession #
Q9XSB5
GenBank Nucleotide #
NM_174051.3
NCBI Official Full Name
estrogen receptor beta
NCBI Official Symbol
ESR2
NCBI Official Synonym Symbols
ERB
UniProt Protein Name
Estrogen receptor beta
UniProt Synonym Protein Names
Nuclear receptor subfamily 3 group A member 2
Protein Family
Estrogen receptor
UniProt Gene Name
ESR2
UniProt Synonym Gene Names
NR3A2; ER-beta
NCBI Protein Information
estrogen receptor beta

UniProt Comments for ESR2

Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1 (ER-alpha), and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. May play a role in ovarian follicular growth and maturation.

Research Articles on ESR2

1. The mRNA expression of ER-alpha and ER-beta in the hypothalamus of developing male and female bovines, is reported.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ESR2 antibody

 Products by Pathway  Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 Nuclear Receptor Transcription Pathway antibodies  Nuclear Receptor Transcription Pathway Diagram
 Nuclear Receptors Pathway antibodies  Nuclear Receptors Pathway Diagram
 Prolactin Signaling Pathway antibodies  Prolactin Signaling Pathway Diagram
 Prolactin Signaling Pathway antibodies  Prolactin Signaling Pathway Diagram

Diseases associated with anti-ESR2 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >77 publications with ESR2 and Neoplasms
 Breast Neoplasms Antibodies  >27 publications with ESR2 and Breast Neoplasms
 Cardiovascular Diseases Antibodies  >27 publications with ESR2 and Cardiovascular Diseases
 Genital Diseases, Male Antibodies  >22 publications with ESR2 and Genital Diseases, Male
 Colorectal Neoplasms Antibodies  >13 publications with ESR2 and Colorectal Neoplasms
 Endometriosis Antibodies  >11 publications with ESR2 and Endometriosis
 Infertility, Female Antibodies  >11 publications with ESR2 and Infertility, Female
 Congenital Abnormalities Antibodies  >10 publications with ESR2 and Congenital Abnormalities
 Hypertension Antibodies  >10 publications with ESR2 and Hypertension
 Carcinoma Antibodies  >10 publications with ESR2 and Carcinoma
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