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CTSD Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS419715

This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but… More details

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Product Overview

Product Name
CTSD, Polyclonal Antibody
Full Product Name
Anti-CTSD Antibody
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Specificity
Western blot analysis of extracts of various cell lines, using CTSD antibody. Immunohistochemistry of paraffin-embedded rat lung using CTSD antibody at dilution of 1:200 (400x lens). Immunohistochemistry of paraffin-embedded human stomach cancer using CTSD antibody at dilution of 1:200 (400x lens).
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
44,552 Da
OMIM
M11233 mRNA
Immunogen
Recombinant Protein of human CTSD
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Applications Tested/Suitable for anti-CTSD antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CTSD antibody
WB: 1:500-1:2000
IHC: 1:50-1:200

Western Blot (WB) of anti-CTSD antibody

Rabbit Anti-CTSD Polyclonal Antibody – Cat# MBS419715

Immunohistochemistry (IHC) of anti-CTSD antibody

Rabbit Anti-CTSD Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS419715

Immunohistochemistry (IHC) of anti-CTSD antibody

Rabbit Anti-CTSD Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS419715

Other Notes

Small volumes of anti-CTSD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CTSD purchase

MBS419715 is an antibody targeting CTSD. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CTSD. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
CTSD
NCBI Official Synonym Full Names
cathepsin D
NCBI Official Symbol
CTSD
NCBI Official Synonym Symbols
CPSD; CLN10; HEL-S-130P
UniProt Protein Name
Cathepsin D
UniProt Gene Name
CTSD
UniProt Synonym Gene Names
CPSD
NCBI Protein Information
cathepsin D

NCBI Summary for CTSD

This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]
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UniProt Comments for CTSD

CTSD: Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. Consists of a light chain and a heavy chain. Belongs to the peptidase A1 family.

Protein type: Autophagy; EC 3.4.23.5; Motility/polarity/chemotaxis; Protease

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: extracellular matrix; extracellular region; extracellular space; lipid raft; lysosomal lumen; lysosome

Molecular Function: cysteine-type endopeptidase activity; protein binding; serine-type endopeptidase activity

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; autophagy; collagen catabolic process; protein catabolic process

Disease: Ceroid Lipofuscinosis, Neuronal, 10
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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