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INADL Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421226

MBS421226 is an antibody targeting INADL. Also known as Goat anti-INADL/PATJ Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human, Dog, Pig, Cow. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
INADL/PATJ, Polyclonal Antibody
Full Product Name
Goat anti-INADL/PATJ Antibody
Product Gene Name
Product Synonym Gene Name
PATJ
Product Synonym Names
INADL; PATJ; PDZ domain protein (Drosophila inaD-like); protein associated to tight junctions; InaD-like (Drosophila); RP4-537K17.1; Cipp; FLJ26982; InaD-like; InaD-like; PALS1-associated tight junction protein; PDZ domain protein; channel-interacting PDZ; INADL antibody; PATJ antibody; PDZ domain protein (Drosophila inaD-like) antibody; protein associated to tight junctions antibody; InaD-like (Drosophila) antibody; RP4-537K17.1 antibody; Cipp antibody; FLJ26982 antibody; InaD-like antibody; InaD-like antibody; PALS1-associated tight junction protein antibody; PDZ domain protein antibody; channel-interacting PDZ domain protein antibody; inactivation no after-potential D-like protein antibody; INADL / PATJ
Immunogen Sequence
PENPATDKLQ VLQ
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human, Dog, Pig, Cow
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
Molecular Weight
125,231 Da
OMIM
603199
Immunogen
Peptide with sequence PENPATDKLQVLQ-C, from the N Terminus of the protein sequence according to NP_795352.2.
Epitope
N Terminus
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-INADL antibody
Peptide ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-INADL antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Immunohistochemistry: In paraffin embedded Human Testis shows strong staining of spermatids. Recommended concentration, 3-6ug/ml.
Western Blot: Preliminary experiments in Human Brain and Kidney lysates consistently showed a strong band at 100kDa followed by bands at ~55kDa, 45kDa and 40kDa at 1ug/ml. Please note that currently we cannot find an explanation in the literature for the bands we observe given the predicted size of approx.196Kda according to NP_795352.2.

Immunohistochemistry (IHC) of anti-INADL antibody

(3.8ug/ml) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Goat Anti-INADL Polyclonal Antibody – Cat# MBS421226

Other Notes

Small volumes of anti-INADL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for INADL. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
inaD-like protein
NCBI Official Synonym Full Names
PATJ, crumbs cell polarity complex component
NCBI Official Symbol
PATJ
NCBI Official Synonym Symbols
Cipp; INADL; hINADL; InaD-like
UniProt Protein Name
InaD-like protein
UniProt Synonym Protein Names
Pals1-associated tight junction protein; Protein associated to tight junctions
UniProt Gene Name
INADL
UniProt Synonym Gene Names
; Inadl protein; hINADL
UniProt Entry Name
INADL_HUMAN
NCBI Protein Information
inaD-like protein

NCBI Summary for INADL

This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors. [provided by RefSeq, Jul 2008]
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UniProt Comments for INADL

INADL: Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 1p31.3

Cellular Component: apical plasma membrane; perinuclear region of cytoplasm; plasma membrane; protein complex; tight junction

Molecular Function: protein binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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