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BDH2 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421597

MBS421597 is an antibody targeting BDH2. Also known as Goat anti-BDH2/DHRS6 (aa 92 to 103) Antibody. Reactive in Expected from sequence similarity: Human, Mouse, Rat, Cow. Host: Goat. More details

$305 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BDH2/DHRS6, Polyclonal Antibody
Full Product Name
Goat anti-BDH2/DHRS6 (aa 92 to 103) Antibody
Product Gene Name
anti-BDH2 antibody
Product Synonym Gene Name
DHRS6
Product Synonym Names
Goat Anti-BDH2 / DHRS6 (aa 60 to 71) Antibody; BDH2; 3-hydroxybutyrate dehydrogenase, type 2; DHRS6; EFA6R; FLJ13261; PRO20933; UCPA-OR; UNQ6308; dehydrogenase/reductase (SDR family) member 6; oxidoreductase UCPA; BDH2 antibody; 3-hydroxybutyrate dehydrogenase; type 2 antibody; DHRS6 antibody; EFA6R antibody; FLJ13261 antibody; PRO20933 antibody; UCPA-OR antibody; UNQ6308 antibody; dehydrogenase/reductase (SDR family) member 6 antibody; oxidoreductase UCPA antibody; BDH2 / DHRS6 (aa 92 to 103)
Immunogen Sequence
DCEEKDWDFS MN
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Cow
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
BDH2 / DHRS6 peptide (MBS425086) is used for blocking the activity of BDH2/DHRS6 antibody (MBS421597)
Molecular Weight
15,626 Da
Immunogen
Peptide with sequence DCEEKDWDFSMN, from the internal region of the protein sequence according to NP_064524.3.
Epitope
Internal region
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-BDH2 antibody
Peptide ELISA (EIA)
Application Notes for anti-BDH2 antibody
Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Preliminary experiments in Human Brain (Cerebellum), Liver and Kidney lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).

Other Notes

Small volumes of anti-BDH2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BDH2. It may not necessarily be applicable to this product.

NCBI GI #
66933014
NCBI GeneID
56898
NCBI Accession #
NP_064524.3
UniProt Secondary Accession #
Q503A0; Q6IA46; Q6UWD3; Q9H8S8; Q9NRX8; A8K295; B4DUF6
UniProt Related Accession #
Q9BUT1
GenBank Nucleotide #
NM_020139.3
NCBI Official Full Name
3-hydroxybutyrate dehydrogenase type 2
NCBI Official Synonym Full Names
3-hydroxybutyrate dehydrogenase, type 2
NCBI Official Symbol
BDH2
NCBI Official Synonym Symbols
DHRS6; EFA6R; SDR15C1; UCPA-OR; UNQ6308; PRO20933
UniProt Protein Name
3-hydroxybutyrate dehydrogenase type 2
UniProt Synonym Protein Names
Dehydrogenase/reductase SDR family member 6; Oxidoreductase UCPA; R-beta-hydroxybutyrate dehydrogenase; Short chain dehydrogenase/reductase family 15C member 1
Protein Family
3-hydroxybutyrate dehydrogenase
UniProt Gene Name
BDH2
UniProt Synonym Gene Names
DHRS6; SDR15C1
UniProt Entry Name
BDH2_HUMAN
NCBI Protein Information
3-hydroxybutyrate dehydrogenase type 2

UniProt Comments for BDH2

DHRS6: Dehydrogenase that mediates the formation of 2,5- dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron homeostasis and transport. Also acts as a 3-hydroxybutyrate dehydrogenase. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Carbohydrate Metabolism - butanoate; Lipid Metabolism - synthesis and degradation of ketone bodies; EC 1.1.1.30; Oxidoreductase

Chromosomal Location of Human Ortholog: 4q24

Cellular Component: cytoplasm; cytosol; mitochondrion

Molecular Function: 3-hydroxybutyrate dehydrogenase activity; NAD binding; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

Biological Process: epithelial cell differentiation; fatty acid beta-oxidation; heme metabolic process; iron ion homeostasis; ketone body biosynthetic process; siderophore biosynthetic process
Show more

Research Articles on BDH2

1. intracellular expression in macrophages is downregulated by stress and inflammation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-BDH2 antibody

 Products by Pathway  Pathway Diagram
 Butanoate Metabolism Pathway antibodies  Butanoate Metabolism Pathway Diagram
 Butanoate Metabolism Pathway antibodies  Butanoate Metabolism Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Ketone Body Metabolism Pathway antibodies  Ketone Body Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Synthesis And Degradation Of Ketone Bodies Pathway antibodies  Synthesis And Degradation Of Ketone Bodies Pathway Diagram
 Synthesis And Degradation Of Ketone Bodies Pathway antibodies  Synthesis And Degradation Of Ketone Bodies Pathway Diagram
 Synthesis Of Ketone Bodies Pathway antibodies  Synthesis Of Ketone Bodies Pathway Diagram

Diseases associated with anti-BDH2 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >2 publications with BDH2 and Inflammation
 Breast Neoplasms Antibodies  >1 publications with BDH2 and Breast Neoplasms
 Disease Models, Animal Antibodies  >1 publications with BDH2 and Disease Models, Animal
 Hypertension Antibodies  >1 publications with BDH2 and Hypertension
 Fibrosis Antibodies  >1 publications with BDH2 and Fibrosis

Organs/Tissues associated with anti-BDH2 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4 publications with BDH2 and Blood
 Eye Antibodies  >1 publications with BDH2 and Eye
 Connective Tissue Antibodies  >1 publications with BDH2 and Connective Tissue
 Spleen Antibodies  >1 publications with BDH2 and Spleen
 Adipose Tissue Antibodies  >1 publications with BDH2 and Adipose Tissue
 Liver Antibodies  >1 publications with BDH2 and Liver
 Testis Antibodies  >1 publications with BDH2 and Testis
 Brain Antibodies  >1 publications with BDH2 and Brain
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