Goat Anti-JUNB Polyclonal Antibody – Cat# MBS421724

(0.3ug/ml) staining of Human Breast Cancer lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

JUNB Antibody – Goat Polyclonal

Name: JUNB Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS421724
Price: 450 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421724

MBS421724 is an antibody targeting JUNB. Also known as Goat anti-JUNB Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Cow, Dog. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

JUNB, Polyclonal Antibody

Full Product Name

Goat anti-JUNB Antibody

Product Gene Name

anti-JUNB antibody

Product Synonym Names

JUNB; jun B proto-oncogene; AP-1; activator protein 1; JUNB antibody; jun B proto-oncogene antibody; AP-1 antibody; activator protein 1 antibody

Immunogen Sequence

TLKAENAGLS STAG

Clonality

Polyclonal

Host

Goat

Species Reactivity

Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Cow, Dog

Form/Format

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Purity/Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

100ug specific antibody in 200ul (lot specific)

Preparation and Storage

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Antibody/Peptide Pairs

JUNB peptide (MBS426475) is used for blocking the activity of JUNB antibody (MBS421724)

Molecular Weight

35,879 Da

OMIM

165161

Immunogen

Peptide with sequence C-TLKAENAGLSSTAG, from the internal region of the protein sequence according to NP_002220.1.

Epitope

Internal region

Note

This antibody may also cross-react with human, mouse, rat, cow, dog JUN (GeneID: 3725, 16476, 24516, 280831, 609429).

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-JUNB antibody

Peptide ELISA (EIA), Western Blot (WB)

Application Notes for anti-JUNB antibody

Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Approx 35kDa band observed in Human Breast cancer lysates (calculated MW of 35.9kDa according to NP_002220.1). Recommended concentration: 0.3-1ug/ml.

Other Notes

Small volumes of anti-JUNB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for JUNB. It may not necessarily be applicable to this product.

NCBI GI #

4504809

NCBI GeneID

3726

NCBI Accession #

NP_002220.1

UniProt Secondary Accession #

Q96GH3

UniProt Related Accession #

P17275

GenBank Nucleotide #

NM_002229.2

NCBI Official Full Name

transcription factor jun-B

NCBI Official Synonym Full Names

JunB proto-oncogene, AP-1 transcription factor subunit

NCBI Official Symbol

JUNB

NCBI Official Synonym Symbols

AP-1

UniProt Protein Name

Transcription factor jun-B

Protein Family

Transcription factor

UniProt Gene Name

JUNB

UniProt Entry Name

JUNB_HUMAN

NCBI Protein Information

transcription factor jun-B

UniProt Comments for JUNB

JunB: Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'. Binds DNA as an homodimer or as an heterodimer with another member of the Jun/Fos family. Interacts with ITCH (via its WW domains). By growth factors. Belongs to the bZIP family. Jun subfamily.

Protein type: Transcription factor; Motility/polarity/chemotaxis; Oncoprotein

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: chromatin; nuclear chromatin; nucleoplasm; transcription factor complex

Molecular Function: DNA binding; protein binding; transcription coactivator activity; transcription corepressor activity; transcription factor binding

Biological Process: cellular response to hormone stimulus; decidualization; embryonic process involved in female pregnancy; negative regulation of transcription from RNA polymerase II promoter; osteoblast differentiation; osteoblast proliferation; osteoclast differentiation; positive regulation of cell differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; response to cAMP; response to corticosterone stimulus; response to cytokine stimulus; response to drug; response to light stimulus; response to lipopolysaccharide; response to mechanical stimulus; response to peptide hormone stimulus; response to progesterone stimulus; response to radiation; transcription from RNA polymerase II promoter; trophectodermal cell differentiation; vasculogenesis

Research Articles on JUNB

1. The MAPK pathway plays a primary role in the control of JUNB gene expression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-JUNB antibody

Reference Product	PubMed Publications
FOS antibody	>733 publications with JUNB and FOS
FOSB antibody	>218 publications with JUNB and FOSB
FOSL2 antibody	>38 publications with JUNB and FOSL2
SMAD3 antibody	>26 publications with JUNB and SMAD3
FOSL1 antibody	>8 publications with JUNB and FOSL1
MAPK8 antibody	>7 publications with JUNB and MAPK8
EP300 antibody	>3 publications with JUNB and EP300
NOS3 antibody	>1 publications with JUNB and NOS3
BATF antibody	>1 publications with JUNB and BATF

Pathways associated with anti-JUNB antibody

Products by Pathway	Pathway Diagram
ATF-2 Transcription Factor Network Pathway antibodies	ATF-2 Transcription Factor Network Pathway Diagram
Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies	Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
Calcium Signaling In The CD4+ TCR Pathway antibodies	Calcium Signaling In The CD4+ TCR Pathway Diagram
Corticotropin-releasing Hormone Pathway antibodies	Corticotropin-releasing Hormone Pathway Diagram
Downstream Signaling In Naive CD8+ T Cells Pathway antibodies	Downstream Signaling In Naive CD8+ T Cells Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Generic Transcription Pathway antibodies	Generic Transcription Pathway Diagram
IL6-mediated Signaling Events Pathway antibodies	IL6-mediated Signaling Events Pathway Diagram
Integrated Pancreatic Cancer Pathway antibodies	Integrated Pancreatic Cancer Pathway Diagram
Oncostatin M Signaling Pathway antibodies	Oncostatin M Signaling Pathway Diagram

Diseases associated with anti-JUNB antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>95 publications with JUNB and Inflammation
Necrosis Antibodies	>70 publications with JUNB and Necrosis
Nervous System Diseases Antibodies	>55 publications with JUNB and Nervous System Diseases
Disease Models, Animal Antibodies	>52 publications with JUNB and Disease Models, Animal
Cardiovascular Diseases Antibodies	>45 publications with JUNB and Cardiovascular Diseases
Brain Diseases Antibodies	>37 publications with JUNB and Brain Diseases
Neoplasms, Experimental Antibodies	>32 publications with JUNB and Neoplasms, Experimental
Liver Neoplasms Antibodies	>32 publications with JUNB and Liver Neoplasms
Fibrosis Antibodies	>18 publications with JUNB and Fibrosis
Lung Neoplasms Antibodies	>17 publications with JUNB and Lung Neoplasms

Organs/Tissues associated with anti-JUNB antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>225 publications with JUNB and Blood
Brain Antibodies	>189 publications with JUNB and Brain
Bone Antibodies	>93 publications with JUNB and Bone
Skin Antibodies	>86 publications with JUNB and Skin
Liver Antibodies	>85 publications with JUNB and Liver
Lung Antibodies	>62 publications with JUNB and Lung
Vascular Antibodies	>62 publications with JUNB and Vascular
Nerve Antibodies	>60 publications with JUNB and Nerve
Bone Marrow Antibodies	>47 publications with JUNB and Bone Marrow
Kidney Antibodies	>39 publications with JUNB and Kidney