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DSCR2/PSMG1 (PSMG1) Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421861

MBS421861 is an antibody targeting PSMG1. Also known as Goat anti-DSCR2/PSMG1 Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow, Rabbit. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DSCR2/PSMG1, Polyclonal Antibody
Full Product Name
Goat anti-DSCR2/PSMG1 Antibody
Product Gene Name
Product Synonym Gene Name
DSCR2
Product Synonym Names
PSMG1; proteasome (prosome, macropain) assembly chaperone 1; C21LRP; DSCR2; LRPC21; PAC1; Down syndrome critical region gene 2; Down syndrome critical region protein 2; chromosome 21 leucine-rich protein; leucine rich protein C21-LRP; proteasome assemblin; PSMG1 antibody; proteasome (prosome; macropain) assembly chaperone 1 antibody; C21LRP antibody; DSCR2 antibody; LRPC21 antibody; PAC1 antibody; Down syndrome critical region gene 2 antibody; Down syndrome critical region protein 2 antibody; chromosome 21 leucine-rich protein antibody; leucine rich protein C21-LRP antibody; proteasome assembling chaperone 1 antibody; DSCR2 / PSMG1
Immunogen Sequence
KLMTTNEIQS NIYT
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow, Rabbit
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
Molecular Weight
30,288 Da
OMIM
605296
Immunogen
Peptide with sequence C-KLMTTNEIQSNIYT, from the C Terminus of the protein sequence according to NP_003711.1; NP_982257.1.
Epitope
C Terminus
Note
This antibody is expected to recognize both reported isoforms (NP_003711.1; NP_982257.1.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-PSMG1 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-PSMG1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Approx.30kDa band observed in lysates in Jurkat (calculated MW of 30.3kDa according to NP_982257.1). Recommended concentration: 0.3-1ug/ml.

Western Blot (WB) of anti-PSMG1 antibody

(0.3ug/ml) staining of Jurkat lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-PSMG1 Polyclonal Antibody – Cat# MBS421861

Other Notes

Small volumes of anti-PSMG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PSMG1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
proteasome assembly chaperone 1 isoform a
NCBI Official Synonym Full Names
proteasome assembly chaperone 1
NCBI Official Symbol
PSMG1
NCBI Official Synonym Symbols
PAC1; DSCR2; PAC-1; C21LRP; LRPC21
UniProt Protein Name
Proteasome assembly chaperone 1
UniProt Synonym Protein Names
Chromosome 21 leucine-rich protein; C21-LRP; Down syndrome critical region protein 2
UniProt Gene Name
PSMG1
UniProt Synonym Gene Names
C21LRP; DSCR2; PAC1; PAC-1; C21-LRP
UniProt Entry Name
PSMG1_HUMAN
NCBI Protein Information
proteasome assembly chaperone 1

UniProt Comments for PSMG1

DSCR2: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. Belongs to the PSMG1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: cytoplasm; endoplasmic reticulum; Golgi apparatus; nucleoplasm; nucleus

Molecular Function: protein binding

Biological Process: granule cell precursor proliferation; proteasome assembly
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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