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MRGPRX3 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS421889

MBS421889 is an antibody targeting MRGPRX3. Also known as Goat anti-MRGPRX3/MRGX3 Antibody. Reactive in Expected from sequence similarity: Human. Host: Goat. More details

$305 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MRGPRX3/MRGX3, Polyclonal Antibody
Full Product Name
Goat anti-MRGPRX3/MRGX3 Antibody
Product Gene Name
Product Synonym Gene Name
MRGX3
Product Synonym Names
MRGPRX3; MAS-related GPR, member X3; GPCR; MRGX3; SNSR1; G protein-coupled receptor MRGX3; G protein-coupled receptor SNSR1; G protein-coupled receptor SNSR2; mas-related GPCR member X3; MRGPRX3 antibody; MAS-related GPR; member X3 antibody; GPCR antibody; MRGX3 antibody; SNSR1 antibody; G protein-coupled receptor MRGX3 antibody; G protein-coupled receptor SNSR1 antibody; G protein-coupled receptor SNSR2 antibody; mas-related GPCR member X3 antibody; MRGPRX3 / MRGX3
Immunogen Sequence
QLPQETLELS GSRL
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
Molecular Weight
36,483 Da
OMIM
607229
Immunogen
Peptide with sequence C-QLPQETLELSGSRL, from the Internal region of the protein sequence according to NP_473372.2.
Epitope
Internal region
Note
This antibody may cross-react with human MRGPRX1 and X4 (GeneID: 259249, 117196; MW: 36.25kDa and 36.43kDa).
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-MRGPRX3 antibody
Peptide ELISA (EIA)
Application Notes for anti-MRGPRX3 antibody
Peptide ELISA: Antibody detection limit dilution 1: 4000.
Western Blot: Not yet tested. At this stage we are dependent on researchers in the field for further characterization of this product. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product.

Other Notes

Small volumes of anti-MRGPRX3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MRGPRX3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
MAS-related GPR, member X3
NCBI Official Synonym Full Names
MAS related GPR family member X3
NCBI Official Symbol
MRGPRX3
NCBI Official Synonym Symbols
GPCR; MRGX3; SNSR1; SNSR2
UniProt Protein Name
Mas-related G-protein coupled receptor member X3
UniProt Synonym Protein Names
Sensory neuron-specific G-protein coupled receptor 1/2
UniProt Gene Name
MRGPRX3
UniProt Synonym Gene Names
MRGX3; SNSR1; SNSR2
UniProt Entry Name
MRGX3_HUMAN
NCBI Protein Information
mas-related G-protein coupled receptor member X3

NCBI Summary for MRGPRX3

This gene encodes a member of the mas-related/sensory neuron specific subfamily of G protein coupled receptors. The encoded protein may be involved in sensory neuron regulation and in the modulation of pain. [provided by RefSeq, Oct 2009]

UniProt Comments for MRGPRX3

MRGPRX3: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins. Belongs to the G-protein coupled receptor 1 family. Mas subfamily.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1

Chromosomal Location of Human Ortholog: 11p15.1

Cellular Component: integral to plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-MRGPRX3 antibody

Organs/Tissues associated with anti-MRGPRX3 antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >1 publications with MRGPRX3 and Eye
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