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SEC23A Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422056

MBS422056 is an antibody targeting SEC23A. Also known as Goat anti-SEC23A Antibody. Reactive in Tested: Mouse; Expected from sequence similarity: Human, Mouse, Rat, Horse, Dog, Cow. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SEC23A, Polyclonal Antibody
Full Product Name
Goat anti-SEC23A Antibody
Product Gene Name
anti-SEC23A antibody
Product Synonym Names
SEC23A; Sec23 homolog A (S. cerevisiae); CLSD; MGC26267; SEC23-related protein A; protein transport protein SEC23A; transport protein Sec23; SEC23A antibody; Sec23 homolog A (S. cerevisiae) antibody; CLSD antibody; MGC26267 antibody; SEC23-related protein A antibody; protein transport protein SEC23A antibody; transport protein Sec23 antibody
Immunogen Sequence
ANRAATTGHV ID
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Mouse; Expected from sequence similarity: Human, Mouse, Rat, Horse, Dog, Cow
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
SEC23A peptide (MBS426354) is used for blocking the activity of SEC23A antibody (MBS422056)
OMIM
607812
Immunogen
Peptide with sequence C-ANRAATTGHVID, from the internal region of the protein sequence according to NP_006355.2.
Epitope
Internal region
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-SEC23A antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-SEC23A antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Approx 100kDa band observed in lysates of NIH3T3 (calculated MW of 86.2kDa according to Human NP_006355.2 and to Mouse NP_033173.2). Recommended concentration: 1-3ug/ml.

Western Blot (WB) of anti-SEC23A antibody

(2ug/ml) staining of NIH3T3 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-SEC23A Polyclonal Antibody – Cat# MBS422056

Other Notes

Small volumes of anti-SEC23A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SEC23A. It may not necessarily be applicable to this product.

NCBI GI #
38202214
NCBI GeneID
10484
NCBI Accession #
NP_006355.2
UniProt Secondary Accession #
Q8NE16; B2R5P4; B3KXI2
UniProt Related Accession #
Q15436
GenBank Nucleotide #
NM_006364.3
NCBI Official Full Name
protein transport protein Sec23A
NCBI Official Synonym Full Names
Sec23 homolog A, coat complex II component
NCBI Official Symbol
SEC23A
NCBI Official Synonym Symbols
CLSD
UniProt Protein Name
Protein transport protein Sec23A
UniProt Synonym Protein Names
SEC23-related protein A
Protein Family
Protein transport protein
UniProt Gene Name
SEC23A
UniProt Entry Name
SC23A_HUMAN
NCBI Protein Information
protein transport protein Sec23A

NCBI Summary for SEC23A

The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It is part of a protein complex and found in the ribosome-free transitional face of the endoplasmic reticulum (ER) and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER-Golgi protein trafficking. [provided by RefSeq, Jul 2008]
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UniProt Comments for SEC23A

SEC23A: Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex. COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1. Interacts with SEC23IP. Interacts with HTR4. Interacts with SLC6A4. Interacts with SEC16A. Belongs to the SEC23/SEC24 family. SEC23 subfamily.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 14q21.1

Cellular Component: COPII vesicle coat; cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; Golgi membrane; perinuclear region of cytoplasm; smooth endoplasmic reticulum membrane

Molecular Function: protein binding; zinc ion binding

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; COPII coating of Golgi vesicle; ER to Golgi vesicle-mediated transport; intracellular protein transport; vesicle-mediated transport

Disease: Craniolenticulosutural Dysplasia
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Research Articles on SEC23A

1. ALG-2 attenuates COPII budding in vitro and stabilizes the Sec23/Sec31A complex.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SEC23A antibody

 Reference Product  PubMed Publications
 SEC13 antibody  >17 publications with SEC23A and SEC13
 SEC31A antibody  >11 publications with SEC23A and SEC31A
 SAR1A antibody  >8 publications with SEC23A and SAR1A
 SEC24C antibody  >6 publications with SEC23A and SEC24C
 SAR1B antibody  >5 publications with SEC23A and SAR1B
 SEC24D antibody  >4 publications with SEC23A and SEC24D
 SEC24A antibody  >3 publications with SEC23A and SEC24A
 SEC24B antibody  >1 publications with SEC23A and SEC24B

Pathways associated with anti-SEC23A antibody

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway antibodies  Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 COPII (Coat Protein 2) Mediated Vesicle Transport Pathway antibodies  COPII (Coat Protein 2) Mediated Vesicle Transport Pathway Diagram
 COPII Complex Pathway antibodies  COPII Complex Pathway Diagram
 COPII Complex Pathway antibodies  COPII Complex Pathway Diagram
 Cargo Concentration In The ER Pathway antibodies  Cargo Concentration In The ER Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 ER To Golgi Anterograde Transport Pathway antibodies  ER To Golgi Anterograde Transport Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram

Diseases associated with anti-SEC23A antibody

 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >5 publications with SEC23A and Neoplasm Metastasis
 Abnormalities, Multiple Antibodies  >5 publications with SEC23A and Abnormalities, Multiple
 Disease Models, Animal Antibodies  >3 publications with SEC23A and Disease Models, Animal
 Fibrosis Antibodies  >3 publications with SEC23A and Fibrosis
 Genital Diseases, Male Antibodies  >2 publications with SEC23A and Genital Diseases, Male
 Liver Diseases Antibodies  >2 publications with SEC23A and Liver Diseases
 Craniolenticulosutural Dysplasia Antibodies  >2 publications with SEC23A and Craniolenticulosutural Dysplasia
 Neural Tube Defects Antibodies  >1 publications with SEC23A and Neural Tube Defects
 Fatty Liver Antibodies  >1 publications with SEC23A and Fatty Liver
 Kidney Diseases Antibodies  >1 publications with SEC23A and Kidney Diseases

Organs/Tissues associated with anti-SEC23A antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >12 publications with SEC23A and Bone
 Connective Tissue Antibodies  >7 publications with SEC23A and Connective Tissue
 Liver Antibodies  >7 publications with SEC23A and Liver
 Embryonic Tissue Antibodies  >5 publications with SEC23A and Embryonic Tissue
 Pancreas Antibodies  >5 publications with SEC23A and Pancreas
 Muscle Antibodies  >4 publications with SEC23A and Muscle
 Blood Antibodies  >4 publications with SEC23A and Blood
 Skin Antibodies  >3 publications with SEC23A and Skin
 Kidney Antibodies  >2 publications with SEC23A and Kidney
 Salivary Gland Antibodies  >2 publications with SEC23A and Salivary Gland
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