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ARL4D Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422217

MBS422217 is an antibody targeting ARL4D. Also known as Goat anti-ARL4D Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human, Mouse, Dog, Cow. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ARL4D, Polyclonal Antibody
Full Product Name
Goat anti-ARL4D Antibody
Product Gene Name
Product Synonym Names
ARL4D; ADP-ribosylation factor-like 4D; ARF4L; ARL6; ADP-ribosylation factor 4-like; ADP-ribosylation factor-like 6; ARL4D antibody; ADP-ribosylation factor-like 4D antibody; ARF4L antibody; ARL6 antibody; ADP-ribosylation factor 4-like antibody; ADP-ribosylation factor-like 6 antibody
Immunogen Sequence
KQDQPGALSA AEVEKR
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human, Mouse, Dog, Cow
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
ARL4D peptide (MBS425465) is used for blocking the activity of ARL4D antibody (MBS422217)
Molecular Weight
22,156 Da
OMIM
600732
Immunogen
Peptide with sequence C-KQDQPGALSAAEVEKR, from the internal region of the protein sequence according to NP_001652.2.
Epitope
Internal region
Note
This antibody is expected not to cross-react to other ARL4 products.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-ARL4D antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-ARL4D antibody
Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Approx.22kDa band observed in Human Lung lysates (calculated MW of 22.2kDa according to NP_001652.2). Recommended concentration: 0.3-1ug/ml.

Western Blot (WB) of anti-ARL4D antibody

(0.5ug/ml) staining of Human Lung lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-ARL4D Polyclonal Antibody – Cat# MBS422217

Other Notes

Small volumes of anti-ARL4D antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ARL4D. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ADP-ribosylation factor-like protein 4D
NCBI Official Synonym Full Names
ADP ribosylation factor like GTPase 4D
NCBI Official Symbol
ARL4D
NCBI Official Synonym Symbols
ARL6; ARF4L
UniProt Protein Name
ADP-ribosylation factor-like protein 4D
UniProt Synonym Protein Names
ADP-ribosylation factor-like protein 4L
UniProt Gene Name
ARL4D
UniProt Synonym Gene Names
ARF4L
UniProt Entry Name
ARL4D_HUMAN
NCBI Protein Information
ADP-ribosylation factor-like protein 4D

NCBI Summary for ARL4D

ADP-ribosylation factor 4D is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4D is closely similar to ARL4A and ARL4C and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. This protein may play a role in membrane-associated intracellular trafficking. Mutations in this gene have been associated with Bardet-Biedl syndrome (BBS). [provided by RefSeq, Jul 2008]
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UniProt Comments for ARL4D

ARL4D: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form. Belongs to the small GTPase superfamily. Arf family.

Protein type: G protein; G protein, monomeric; G protein, monomeric, ARF; Nucleolus

Chromosomal Location of Human Ortholog: 17q21.31

Cellular Component: cytoplasm; nucleolus; plasma membrane

Molecular Function: GTP binding; GTPase activity; protein binding

Biological Process: protein secretion; small GTPase mediated signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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