ALDH1B1 Antibody – Goat Polyclonal

This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems. [provided by RefSeq, Jul 2008]

ALDH1B1: ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. Belongs to the aldehyde dehydrogenase family.

Protein type: Lipid Metabolism - glycerolipid; Carbohydrate Metabolism - ascorbate and aldarate; Amino Acid Metabolism - lysine degradation; Amino Acid Metabolism - tryptophan; EC 1.2.1.3; Secondary Metabolites Metabolism - limonene and pinene degradation; Lipid Metabolism - fatty acid; Oxidoreductase; Carbohydrate Metabolism - propanoate; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Amino Acid Metabolism - arginine and proline; Other Amino Acids Metabolism - beta-alanine; Amino Acid Metabolism - histidine; Carbohydrate Metabolism - pyruvate; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Mitochondrial; Carbohydrate Metabolism - butanoate

Chromosomal Location of Human Ortholog: 9p11.1

Cellular Component: intracellular membrane-bound organelle; mitochondrial matrix; mitochondrion; nucleoplasm

Molecular Function: aldehyde dehydrogenase (NAD) activity

Biological Process: carbohydrate metabolic process; ethanol catabolic process; ethanol oxidation