Goat Anti-ALDH3B1 Polyclonal Antibody – Cat# MBS422396

(0.3ug/ml) staining of K562 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

ALDH3B1 Antibody – Goat Polyclonal

Name: ALDH3B1 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS422396
Price: 450 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422396

MBS422396 is an antibody targeting ALDH3B1. Also known as Goat anti-ALDH3B1 Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ALDH3B1, Polyclonal Antibody

Full Product Name

Goat anti-ALDH3B1 Antibody

Product Gene Name

anti-ALDH3B1 antibody

Product Synonym Names

ALDH3B1; aldehyde dehydrogenase 3 family, member B1; ALDH4; ALDH7; FLJ26433; FLJ34710; aldehyde dehydrogenase 3B1; aldehyde dehydrogenase 7; aldehyde dehydrogenase 3 family; member B1 antibody; aldehyde dehydrogenase 3B1 antibody; aldehyde dehydrogenase 7 antibody; ALDH4 antibody; ALDH7 antibody; FLJ26433 antibody; FLJ34710 antibody; ALDH3B1 antibody

Immunogen Sequence

QDLHKSAFES EVSE

Clonality

Polyclonal

Host

Goat

Species Reactivity

Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow

Form/Format

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Purity/Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

100ug specific antibody in 200ul (lot specific)

Preparation and Storage

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Antibody/Peptide Pairs

ALDH3B1 peptide (MBS427357) is used for blocking the activity of ALDH3B1 antibody (MBS422396)

Molecular Weight

47,683 Da

OMIM

600466

Immunogen

Peptide with sequence C-QDLHKSAFESEVSE, from the internal region of the protein sequence according to NP_000685.1.

Epitope

Internal region

Note

This antibody is expected to recognize isoform a (NP_000685.1) o

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-ALDH3B1 antibody

Peptide ELISA (EIA), Western Blot (WB)

Application Notes for anti-ALDH3B1 antibody

Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Approx 55kDa band observed in Human Peripheral Blood Mononucleocytes and in lysates of cell line K562 (calculated MW of 51.8kDa according to NP_000685.1). Recommended concentration: 0.3-1ug/ml.

Other Notes

Small volumes of anti-ALDH3B1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ALDH3B1. It may not necessarily be applicable to this product.

NCBI GI #

4502043

NCBI GeneID

221

NCBI Accession #

NP_000685.1

UniProt Secondary Accession #

Q53XL5; Q8N515; Q96CK8; A3FMP9

UniProt Related Accession #

P43353

GenBank Nucleotide #

NM_000694.3

NCBI Official Full Name

aldehyde dehydrogenase family 3 member B1 isoform a

NCBI Official Synonym Full Names

aldehyde dehydrogenase 3 family member B1

NCBI Official Symbol

ALDH3B1

NCBI Official Synonym Symbols

ALDH4; ALDH7

UniProt Protein Name

Aldehyde dehydrogenase family 3 member B1

UniProt Synonym Protein Names

Aldehyde dehydrogenase 7

Protein Family

Aldehyde dehydrogenase family

UniProt Gene Name

ALDH3B1

UniProt Synonym Gene Names

ALDH7

UniProt Entry Name

AL3B1_HUMAN

NCBI Protein Information

aldehyde dehydrogenase family 3 member B1

NCBI Summary for ALDH3B1

This gene encodes a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The encoded protein is able to oxidize long-chain fatty aldehydes in vitro, and may play a role in protection from oxidative stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

UniProt Comments for ALDH3B1

ALDH3B1: Oxidizes medium and long chain saturated and unsaturated aldehydes. Metabolizes also benzaldehyde. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short chain aldehydes. May use both NADP(+) and NAD(+) as cofactors. May have a protective role against the cytotoxicity induced by lipid peroxidation. Belongs to the aldehyde dehydrogenase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450; Oxidoreductase; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - histidine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Amino Acid Metabolism - phenylalanine; EC 1.2.1.5

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: cytoplasm; cytosol; plasma membrane; vesicle

Molecular Function: 3-chloroallyl aldehyde dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; aldehyde dehydrogenase [NAD(P)+] activity; protein binding

Biological Process: alcohol metabolic process; aldehyde catabolic process; ethanol catabolic process; lipid metabolic process; sphingolipid biosynthetic process

Research Articles on ALDH3B1

1. the likely physiological function of ALDH3B1 is to oxidize lipid-derived aldehydes generated in the plasma membrane and not to be involved in the sphingolipid metabolism in the endoplasmic reticulum.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ALDH3B1 antibody

Products by Pathway	Pathway Diagram
2'-deoxy-alpha-D-ribose 1-phosphate Degradation Pathway antibodies	2'-deoxy-alpha-D-ribose 1-phosphate Degradation Pathway Diagram
Chemical Carcinogenesis Pathway antibodies	Chemical Carcinogenesis Pathway Diagram
Chemical Carcinogenesis Pathway antibodies	Chemical Carcinogenesis Pathway Diagram
Drug Metabolism - Cytochrome P450 Pathway antibodies	Drug Metabolism - Cytochrome P450 Pathway Diagram
Drug Metabolism - Cytochrome P450 Pathway antibodies	Drug Metabolism - Cytochrome P450 Pathway Diagram
Glycolysis / Gluconeogenesis Pathway antibodies	Glycolysis / Gluconeogenesis Pathway Diagram
Glycolysis / Gluconeogenesis Pathway antibodies	Glycolysis / Gluconeogenesis Pathway Diagram
Histidine Metabolism Pathway antibodies	Histidine Metabolism Pathway Diagram
Histidine Metabolism Pathway antibodies	Histidine Metabolism Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram

Diseases associated with anti-ALDH3B1 antibody

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>2 publications with ALDH3B1 and Breast Neoplasms
Liver Diseases Antibodies	>2 publications with ALDH3B1 and Liver Diseases
Ovarian Diseases Antibodies	>1 publications with ALDH3B1 and Ovarian Diseases
Ovarian Neoplasms Antibodies	>1 publications with ALDH3B1 and Ovarian Neoplasms
Lung Neoplasms Antibodies	>1 publications with ALDH3B1 and Lung Neoplasms
Fatty Liver Antibodies	>1 publications with ALDH3B1 and Fatty Liver
Kidney Diseases Antibodies	>1 publications with ALDH3B1 and Kidney Diseases

Organs/Tissues associated with anti-ALDH3B1 antibody

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>2 publications with ALDH3B1 and Testis
Eye Antibodies	>2 publications with ALDH3B1 and Eye
Kidney Antibodies	>2 publications with ALDH3B1 and Kidney
Lung Antibodies	>2 publications with ALDH3B1 and Lung
Bone Antibodies	>1 publications with ALDH3B1 and Bone
Pancreas Antibodies	>1 publications with ALDH3B1 and Pancreas
Brain Antibodies	>1 publications with ALDH3B1 and Brain
Bone Marrow Antibodies	>1 publications with ALDH3B1 and Bone Marrow
Thyroid Antibodies	>1 publications with ALDH3B1 and Thyroid