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DNAH8 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422447

MBS422447 is an antibody targeting DNAH8. Also known as Goat anti-DNAH8 (aa1738-1749) Antibody. Reactive in Expected from sequence similarity: Human, Mouse, Rat, Dog, Rabbit. Host: Goat. More details

$305 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DNAH8, Polyclonal Antibody
Full Product Name
Goat anti-DNAH8 (aa1738-1749) Antibody
Product Gene Name
Product Synonym Names
Goat Anti-DNAH8 (aa107 -117) Antibody; DNAH8; dynein, axonemal, heavy chain 8; ATPase; FLJ25850; FLJ36115; FLJ36334; hdhc9; dynein, axonemal, heavy polypeptide 8; ATPase antibody; dynein; axonemal; heavy chain 8 antibody; dynein; axonemal; heavy polypeptide 8 antibody; FLJ25850 antibody; FLJ36115 antibody; FLJ36334 antibody; hdhc9 antibody; DNAH8 antibody; DNAH8 (aa1738-1749)
Immunogen Sequence
SQTTHDLSKF DR
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Rabbit
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
DNAH8 peptide (MBS427336) is used for blocking the activity of DNAH8 antibody (MBS422447)
Molecular Weight
– Da
OMIM
603337
Immunogen
Peptide with sequence C-SQTTHDLSKFDR, from the internal region of the protein sequence according to NP_001362.2.
Epitope
Internal region
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-DNAH8 antibody
Peptide ELISA (EIA)
Application Notes for anti-DNAH8 antibody
Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Not yet tested - our routinely used western blotting protocol does not allow detection of proteins as large as the calculated size of 515kDa according to NP_001362.2. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product.

Other Notes

Small volumes of anti-DNAH8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DNAH8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Synonym Full Names
dynein axonemal heavy chain 8
NCBI Official Symbol
DNAH8
NCBI Official Synonym Symbols
hdhc9; ATPase
UniProt Protein Name
Dynein heavy chain 8, axonemal
UniProt Synonym Protein Names
Axonemal beta dynein heavy chain 8; Ciliary dynein heavy chain 8
Protein Family
UniProt Gene Name
DNAH8
UniProt Entry Name
DYH8_HUMAN
NCBI Protein Information
dynein heavy chain 8, axonemal

NCBI Summary for DNAH8

The protein encoded by this gene is a heavy chain of an axonemal dynein involved in sperm and respiratory cilia motility. Axonemal dyneins generate force through hydrolysis of ATP and binding to microtubules. [provided by RefSeq, Jan 2012]

UniProt Comments for DNAH8

DNAH8: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly. Belongs to the dynein heavy chain family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Microtubule-binding; Motor

Chromosomal Location of Human Ortholog: 6p21.2

Cellular Component: axonemal dynein complex; cytoplasm; dynein complex; microtubule

Molecular Function: ATP binding; ATPase activity; microtubule motor activity

Biological Process: ciliary or flagellar motility; metabolic process; microtubule-based movement
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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