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BOK Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422701

MBS422701 is an antibody targeting BOK. Also known as Goat anti-BOK Antibody. Reactive in Expected from sequence similarity: Human, Mouse, Cow. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BOK, Polyclonal Antibody
Full Product Name
Goat anti-BOK Antibody
Product Gene Name
Product Synonym Names
BOK; BCL2-related ovarian killer; BCL2L9; BOKL; MGC4631; BCL2L9 antibody; BCL2-related ovarian killer antibody; BOKL antibody; MGC4631 antibody; BOK antibody
Immunogen Sequence
HISLQSEPVV TD
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human, Mouse, Cow
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
BOK peptide (MBS427697) is used for blocking the activity of BOK antibody (MBS422701)
Molecular Weight
23,280 Da
OMIM
605404
Immunogen
Peptide with sequence C-HISLQSEPVVTD, from the internal region of the protein sequence according to NP_115904.1.
Epitope
Internal region
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-BOK antibody
Peptide ELISA (EIA)
Application Notes for anti-BOK antibody
Peptide ELISA: Antibody detection limit dilution 1: 8000.
Western Blot: Preliminary experiments gave bands at approx 55kDa and 20kDa in Human Testis lysates after 1ug/ml antibody staining, and 17kDa in Mouse Spleen and Thymus lysates after 0.3ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 23.3kDa according to NP_115904.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).

Other Notes

Small volumes of anti-BOK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BOK. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
bcl-2-related ovarian killer protein
NCBI Official Synonym Full Names
BCL2-related ovarian killer
NCBI Official Symbol
BOK
NCBI Official Synonym Symbols
BOKL; BCL2L9
UniProt Protein Name
Bcl-2-related ovarian killer protein
UniProt Synonym Protein Names
Bcl-2-like protein 9; Bcl2-L-9
UniProt Gene Name
BOK
UniProt Synonym Gene Names
BCL2L9; hBOK; Bcl2-L-9
UniProt Entry Name
BOK_HUMAN
NCBI Protein Information
bcl-2-related ovarian killer protein

NCBI Summary for BOK

The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family. [provided by RefSeq, Sep 2011]
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UniProt Comments for BOK

BOK: May play a role in apoptosis. Belongs to the Bcl-2 family.

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: cytoplasm; endoplasmic reticulum membrane; Golgi membrane; integral to membrane; mitochondrial membrane; mitochondrial outer membrane; mitochondrion; nucleus

Molecular Function: BH domain binding; protein binding; protein heterodimerization activity; protein homodimerization activity

Biological Process: apoptosis; brain development; caspase activation; cell proliferation; DNA damage response, signal transduction resulting in induction of apoptosis; male gonad development; neuron apoptosis; oligodendrocyte differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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