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Neuron Navigator 2 (NAV2) Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS423347

MBS423347 is an antibody targeting NAV2. Also known as Goat anti-neuron navigator 2 Antibody. Reactive in Expected from sequence similarity: Human. Host: Goat. More details

$305 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
neuron navigator 2 (NAV2), Polyclonal Antibody
Full Product Name
Goat anti-neuron navigator 2 Antibody
Product Gene Name
Product Synonym Names
NAV2; neuron navigator 2; HELAD1; POMFIL2; RAINB1; STEERIN2; UNC53H2; helicase, APC down-regulated 1; pore membrane and/or filament-interacting-like protein 2; retinoic acid inducible gene in neuroblastoma 1; steerin-2; unc-53 homolog 2; NAV2 antibody; neuron navigator 2 antibody; HELAD1 antibody; POMFIL2 antibody; RAINB1 antibody; STEERIN2 antibody; UNC53H2 antibody; helicase; APC down-regulated 1 antibody; pore membrane and/or filament-interacting-like protein 2 antibody; retinoic acid inducible gene in neuroblastoma 1 antibody; steerin-2 antibody; unc-53 homolog 2 antibody; neuron navigator 2; neuron navigator 2
Immunogen Sequence
PELNCKGNGT AQS
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
Molecular Weight
261,102 Da
OMIM
607026
Immunogen
Peptide with sequence PELNCKGNGTAQS, from the internal region of the protein sequence according to NP_892009.3; NP_660093.2; NP_001104488.1; NP_001104489.1; NP_001231892.1.
Epitope
Internal region
Note
This antibody is expected to recognize all reported isoforms (NP_892009.3; NP_660093.2; NP_001104488.1; NP_001104489.1; NP_001231892.1).
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-NAV2 antibody
Peptide ELISA (EIA)
Application Notes for anti-NAV2 antibody
Peptide ELISA: Antibody detection limit dilution 1: 1000.
Western Blot: Preliminary experiments in Human Brain, Kidney and Liver lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).

Other Notes

Small volumes of anti-NAV2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NAV2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
neuron navigator 2 isoform 1
NCBI Official Synonym Full Names
neuron navigator 2
NCBI Official Symbol
NAV2
NCBI Official Synonym Symbols
HELAD1; RAINB1; POMFIL2; UNC53H2; STEERIN2
UniProt Protein Name
Neuron navigator 2
UniProt Synonym Protein Names
Helicase APC down-regulated 1; Pore membrane and/or filament-interacting-like protein 2; Retinoic acid inducible in neuroblastoma 1; Steerin-2; Unc-53 homolog 2; unc53H2
Protein Family
UniProt Gene Name
NAV2
UniProt Synonym Gene Names
HELAD1; KIAA1419; POMFIL2; RAINB1; STEERIN2; unc53H2
UniProt Entry Name
NAV2_HUMAN
NCBI Protein Information
neuron navigator 2

NCBI Summary for NAV2

This gene encodes a member of the neuron navigator gene family, which may play a role in cellular growth and migration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

UniProt Comments for NAV2

NAV2: an actin-binding protein involved in cell migration, actin cytoskeletal remodeling and neuronal development. Belongs to the Nav/unc-53 family. Interacts with Abi1 and the ARP2/3 complex. 13 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal; Actin-binding

Chromosomal Location of Human Ortholog: 11p15.1

Cellular Component: nucleoplasm

Molecular Function: ATP binding; helicase activity; heparin binding; protein binding

Biological Process: glossopharyngeal nerve development; locomotory behavior; metabolic process; optic nerve development; regulation of systemic arterial blood pressure by baroreceptor feedback; sensory perception of smell; sensory perception of sound; vagus nerve development
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Research Articles on NAV2

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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