Goat Anti-SLC26A1 Polyclonal Antibody – Cat# MBS423450

(2ug/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.

SLC26A1 Antibody – Goat Polyclonal

Name: SLC26A1 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS423450
Price: 450 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS423450

MBS423450 is an antibody targeting SLC26A1. Also known as Goat anti-SLC26A1/SAT-1 Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SLC26A1/SAT-1, Polyclonal Antibody

Full Product Name

Goat anti-SLC26A1/SAT-1 Antibody

Product Gene Name

anti-SLC26A1 antibody

Product Synonym Gene Name

SAT-1

Product Synonym Names

SLC26A1; solute carrier family 26 (sulfate transporter), member 1; EDM4; SAT-1; SAT1; sulfate anion tranporter AT1; sulfate anion transporter 1; sulfate/anion transporter SAT-1 protein; SLC26A1 antibody; solute carrier family 26 (sulfate transporter); member 1 antibody; EDM4 antibody; SAT-1 antibody; SAT1 antibody; sulfate anion tranporter AT1 antibody; sulfate anion transporter 1 antibody; sulfate/anion transporter SAT-1 protein antibody; SLC26A1 / SAT-1

Immunogen Sequence

QTARARHREL EATD

Clonality

Polyclonal

Host

Goat

Species Reactivity

Tested: Human; Expected from sequence similarity: Human

Form/Format

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Purity/Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

100ug specific antibody in 200ul (lot specific)

Preparation and Storage

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Antibody/Peptide Pairs

SLC26A1 / SAT-1 peptide (MBS428176) is used for blocking the activity of SLC26A1/SAT-1 antibody (MBS423450)

Molecular Weight

24,962 Da

OMIM

610130

Immunogen

Peptide with sequence C-QTARARHRELEATD, from the C Terminus of the protein sequence according to NP_071325.2; NP_602297.1.

Epitope

C Terminus

Note

This antibody is expected to recognize reported isoform a (NP_071325.2) only. Reported variants represent identical protein: NP_998778.1, NP_071325.2

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-SLC26A1 antibody

Peptide ELISA (EIA), Immunohistochemistry (IHC)

Application Notes for anti-SLC26A1 antibody

Peptide ELISA: Antibody detection limit dilution 1: 4000.
Immunohistochemistry: In paraffin embedded Human Kidney shows strong basal membrane staining in convoluted tubules. Recommended concentration, 2-4ug/ml.

Other Notes

Small volumes of anti-SLC26A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC26A1. It may not necessarily be applicable to this product.

NCBI GI #

20336272

NCBI GeneID

10861

NCBI Accession #

NP_071325.2

NCBI Related Accession #

NP_602297.1

UniProt Secondary Accession #

Q7Z5R3; Q96BK0; A8K9N2

UniProt Related Accession #

Q9H2B4

GenBank Nucleotide #

NM_022042.3

NCBI Official Full Name

sulfate anion transporter 1 isoform a

NCBI Official Synonym Full Names

solute carrier family 26 member 1

NCBI Official Symbol

SLC26A1

NCBI Official Synonym Symbols

EDM4; SAT1; SAT-1

UniProt Protein Name

Sulfate anion transporter 1

UniProt Synonym Protein Names

Solute carrier family 26 member 1

Protein Family

Sulfate anion transporter

UniProt Gene Name

SLC26A1

UniProt Synonym Gene Names

SAT1; SAT-1

UniProt Entry Name

S26A1_HUMAN

NCBI Protein Information

sulfate anion transporter 1

NCBI Summary for SLC26A1

This gene is a member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures, but have markedly different tissue expression patterns. This gene is primarily expressed in the liver, pancreas, and brain. Three splice variants that encode different isoforms have been identified. [provided by RefSeq, Jul 2008]

UniProt Comments for SLC26A1

SLC26A1: High affinity uptake of sulfate. Accepts oxalate, but not succinate as a cosubstrate. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4p16.3

Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function: anion:anion antiporter activity; bicarbonate transmembrane transporter activity; chloride channel activity; chloride transmembrane transporter activity; oxalate transmembrane transporter activity; secondary active sulfate transmembrane transporter activity; sulfate transmembrane transporter activity

Biological Process: 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process; bicarbonate transport; chloride transport; ion transport; oxalate transport; regulation of intracellular pH; regulation of membrane potential; sulfate transport

Research Articles on SLC26A1

1. Screened the SLC26A1 gene in a cohort of 13 individuals with recurrent calcium oxalate urolithiasis, which is the commonest type. DNA sequence analyses showed missense mutations in seven patients.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SLC26A1 antibody

Products by Pathway	Pathway Diagram
Biological Oxidations Pathway antibodies	Biological Oxidations Pathway Diagram
Cytosolic Sulfonation Of Small Molecules Pathway antibodies	Cytosolic Sulfonation Of Small Molecules Pathway Diagram
Glycosaminoglycan Metabolism Pathway antibodies	Glycosaminoglycan Metabolism Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Carbohydrates Pathway antibodies	Metabolism Of Carbohydrates Pathway Diagram
Multifunctional Anion Exchangers Pathway antibodies	Multifunctional Anion Exchangers Pathway Diagram
Phase II Conjugation Pathway antibodies	Phase II Conjugation Pathway Diagram
SLC-mediated Transmembrane Transport Pathway antibodies	SLC-mediated Transmembrane Transport Pathway Diagram
Transmembrane Transport Of Small Molecules Pathway antibodies	Transmembrane Transport Of Small Molecules Pathway Diagram
Transport And Synthesis Of PAPS Pathway antibodies	Transport And Synthesis Of PAPS Pathway Diagram

Diseases associated with anti-SLC26A1 antibody

Disease Name	Pubmed Publications
Hyperoxaluria Antibodies	>12 publications with SLC26A1 and Hyperoxaluria
Kidney Diseases Antibodies	>10 publications with SLC26A1 and Kidney Diseases
Urolithiasis Antibodies	>10 publications with SLC26A1 and Urolithiasis
Fibrosis Antibodies	>5 publications with SLC26A1 and Fibrosis
Neurologic Manifestations Antibodies	>5 publications with SLC26A1 and Neurologic Manifestations
Nephrocalcinosis Antibodies	>4 publications with SLC26A1 and Nephrocalcinosis
Renal Insufficiency Antibodies	>2 publications with SLC26A1 and Renal Insufficiency
Liver Failure, Acute Antibodies	>1 publications with SLC26A1 and Liver Failure, Acute
Cardiovascular Diseases Antibodies	>1 publications with SLC26A1 and Cardiovascular Diseases
Abnormalities, Multiple Antibodies	>1 publications with SLC26A1 and Abnormalities, Multiple

Organs/Tissues associated with anti-SLC26A1 antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>35 publications with SLC26A1 and Kidney
Blood Antibodies	>16 publications with SLC26A1 and Blood
Liver Antibodies	>11 publications with SLC26A1 and Liver
Pancreas Antibodies	>4 publications with SLC26A1 and Pancreas
Brain Antibodies	>4 publications with SLC26A1 and Brain
Embryonic Tissue Antibodies	>2 publications with SLC26A1 and Embryonic Tissue
Lung Antibodies	>1 publications with SLC26A1 and Lung
Ovary Antibodies	>1 publications with SLC26A1 and Ovary