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CLIC1 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS423475

MBS423475 is an antibody targeting CLIC1. Also known as Goat anti-CLIC1/NCC27 (aa45-57) Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CLIC1/NCC27, Polyclonal Antibody
Full Product Name
Goat anti-CLIC1/NCC27 (aa45-57) Antibody
Product Gene Name
Product Synonym Gene Name
NCC27
Product Synonym Names
Goat Anti-CLIC1 / NCC27 Antibody; CLIC1; chloride intracellular channel 1; G6; NCC27; RNCC protein; chloride channel ABP; chloride intracellular channel protein 1; hRNCC; nuclear chloride ion channel 27; nuclear chloride ion channel protein; p64CLCP; regulatory nuclear chloride ion channe; CLIC1 antibody; chloride intracellular channel 1 antibody; G6 antibody; NCC27 antibody; RNCC protein antibody; chloride channel ABP antibody; chloride intracellular channel protein 1 antibody; hRNCC antibody; nuclear chloride ion channel 27 antibody; nuclear chloride ion channel protein antibody; p64CLCP antibody; regulatory nuclear chloride ion channe antibody; CLIC1 / NCC27 (aa45-57)
Immunogen Sequence
TVDTKRRTET VQK
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
Molecular Weight
26,923 Da
OMIM
602872
Immunogen
Peptide with sequence C-TVDTKRRTETVQK, from the internal region of the protein sequence according to NP_001279.2.
Epitope
Internal region
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-CLIC1 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-CLIC1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 4000.
Western Blot: Approx 30kDa band observed in lysates of cell line U937 (calculated MW of 26.9kDa according to NP_001279.2). Recommended concentration: 1-3ug/ml.

Western Blot (WB) of anti-CLIC1 antibody

(2ug/ml) staining of U937 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-CLIC1 Polyclonal Antibody – Cat# MBS423475

Other Notes

Small volumes of anti-CLIC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CLIC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
chloride intracellular channel protein 1
NCBI Official Synonym Full Names
chloride intracellular channel 1
NCBI Official Symbol
CLIC1
NCBI Official Synonym Symbols
G6; NCC27
UniProt Protein Name
Chloride intracellular channel protein 1
UniProt Synonym Protein Names
Chloride channel ABP; Nuclear chloride ion channel 27; NCC27; Regulatory nuclear chloride ion channel protein; hRNCC
UniProt Gene Name
CLIC1
UniProt Synonym Gene Names
G6; NCC27; NCC27; hRNCC
UniProt Entry Name
CLIC1_HUMAN
NCBI Protein Information
chloride intracellular channel protein 1

NCBI Summary for CLIC1

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. [provided by RefSeq, Jul 2008]
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UniProt Comments for CLIC1

CLIC1: Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle. Belongs to the chloride channel CLIC family.

Protein type: Channel, chloride; Membrane protein, integral; Nuclear envelope

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: brush border; cell-cell adherens junction; cytoplasm; extracellular space; membrane; nuclear envelope; nucleus; perinuclear region of cytoplasm; vesicle

Molecular Function: chloride channel activity; glutathione transferase activity; protein binding

Biological Process: chloride transport; glutathione metabolic process; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CLIC1 antibody

 Reference Product  PubMed Publications
 CLCN4 antibody  >1 publications with CLIC1 and CLCN4
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