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SLC7A6 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS423772

MBS423772 is an antibody targeting SLC7A6. Also known as Goat anti-SLC7A6/y+LAT-2 (C Terminus) Antibody. Reactive in Human. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SLC7A6/y+LAT-2, Antibody
Full Product Name
Goat anti-SLC7A6/y+LAT-2 (C Terminus) Antibody
Product Gene Name
Product Synonym Names
SLC7A6; solute carrier family 7 (amino acid transporter light chain, y+L system), member 6; LAT-2; LAT3; y+LAT-2; Y+L amino acid transporter 2; amino acid permease; cationic amino acid transporter, y+ system; solute carrier family 7 (cationic amino acid transporter, y+ system), member 6; solute carrier family 7 member 6; y(+)L-type amino acid transporter 2; y+LAT2
Species Reactivity
Human
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
Molecular Weight
56.8kDa
OMIM
605641
3D Structure
ModBase 3D Structure for Q92536
Immunogen Sequence
Peptide with sequence C-ELDVAEEKKDERKTD, from the C Terminus of the protein sequence according to NP_003974.3.
Peptide Sequence + C
C-ELDVAEEKKDERKTD
Epitope
C Terminus
Note
Reported variants represent identical protein: NP_003974.3, NP_001070253.1
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-SLC7A6 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-SLC7A6 antibody
Pep-ELISA: antibody detection limit dilution 1:32000.
WB: Approx 58-60kDa band observed in Human Heart lysates. Recommended concentration: 0.3-1ug/ml.

Immunohistochemistry (IHC) of anti-SLC7A6 antibody

(0.3ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence
Anti-SLC7A6 Antibody – Cat# MBS423772

Other Notes

Small volumes of anti-SLC7A6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC7A6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Y+L amino acid transporter 2
NCBI Official Synonym Full Names
solute carrier family 7 member 6
NCBI Official Symbol
SLC7A6
NCBI Official Synonym Symbols
LAT3; LAT-2; y+LAT-2
UniProt Protein Name
Y+L amino acid transporter 2
UniProt Synonym Protein Names
Cationic amino acid transporter, y+ system; Solute carrier family 7 member 6; y(+)L-type amino acid transporter 2; Y+LAT2; y+LAT-2
UniProt Gene Name
SLC7A6
UniProt Synonym Gene Names
Y+LAT2; y+LAT-2
NCBI Protein Information
Y+L amino acid transporter 2

UniProt Comments for SLC7A6

Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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