Parathyroid Hormone Related (PTHRP) ELISA Kit for Sheep

Name: Sheep PTHRP ELISA Kit; Parathyroid Hormone Related; MyBioSource
Brand: MyBioSource
SKU: MBS042558
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS042558

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used to determine the level of PTHRP (hereafter termed "analyte") in… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Parathyroid Hormone Related Protein (PTHRP), ELISA Kit

Full Product Name

Sheep Parathyroid Hormone Related Protein (PTHRP) ELISA Kit

Product Gene Name

PTHRP elisa kit

Species Reactivity

Sheep

Assay Type

Quantitative Sandwich

Detection Range

31.2pg/ml-1000pg/ml

Sensitivity

5.0pg/ml

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

20,100 Da

Other Notes

Small volumes of PTHRP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTHRP purchase

MBS042558 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Parathyroid Hormone Related Protein (PTHRP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PTHRP. The ELISA analytical biochemical technique of the MBS042558 kit is based on PTHRP antibody-PTHRP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PTHRP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PTHRP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for PTHRP. It may not necessarily be applicable to this product.

NCBI GI #

148747356

NCBI GeneID

19227

NCBI Accession #

NP_032996.2

UniProt Related Accession #

P22858

GenBank Nucleotide #

NM_008970.4

NCBI Official Full Name

parathyroid hormone-related protein preproprotein

NCBI Official Synonym Full Names

parathyroid hormone-like peptide

NCBI Official Symbol

Pthlh

NCBI Official Synonym Symbols

PLP; Pthrp; PTH-like

UniProt Protein Name

Parathyroid hormone-related protein

UniProt Synonym Protein Names

Parathyroid hormone-like protein; PLP

UniProt Gene Name

Pthlh

UniProt Synonym Gene Names

Pthrp; PTH-rP; PTHrP; PLP

UniProt Entry Name

PTHR_MOUSE

NCBI Protein Information

parathyroid hormone-related protein

NCBI Summary for PTHRP

This gene encodes a member of the parathyroid family of hormones that possesses distinct paracrine and intracrine signaling roles such as regulation of circulating calcium, transplacental calcium transport, osteoclast inhibition, renal bicarbonate excretion and regulation of apoptosis. The encoded protein undergoes proteolytic processing to generate multiple active peptides with distinct signaling functions. The homozygous deletion of this gene leads to death shortly after birth with a chondrodystrophic phenotype characterized by premature chondrocyte differentiation and accelerated bone formation. [provided by RefSeq, Jul 2015]

UniProt Comments for PTHRP

PTHrP: a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Three alternatively spliced isoforms have been described.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: cytoplasm; extracellular space; Golgi apparatus; intracellular; nucleoplasm

Molecular Function: hormone activity; peptide hormone receptor binding

Biological Process: alveolus development; bone mineralization; endochondral ossification; endoderm development; epithelial cell differentiation; G-protein signaling, adenylate cyclase activating pathway; negative regulation of chondrocyte differentiation; negative regulation of transcription factor activity; osteoblast development; positive regulation of cAMP biosynthetic process; positive regulation of cell proliferation; protein processing; regulation of gene expression; skeletal development; surfactant homeostasis

Research Articles on PTHRP

1. fluoride might be able to affect calcium homeostasis by regulating PTH, PTHrP, and CaSR

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PTHRP elisa kit

Reference Product	PubMed Publications
Ihh elisa kit	>26 publications with PTHRP and Ihh
Pth1r elisa kit	>19 publications with PTHRP and Pth1r
Runx2 elisa kit	>8 publications with PTHRP and Runx2
Pth2r elisa kit	>4 publications with PTHRP and Pth2r
Ibsp elisa kit	>3 publications with PTHRP and Ibsp
Gnas elisa kit	>1 publications with PTHRP and Gnas
Ptger4 elisa kit	>1 publications with PTHRP and Ptger4

Pathways associated with PTHRP elisa kit

Products by Pathway	Pathway Diagram
Class B/2 (Secretin Family Receptors) Pathway antibodies	Class B/2 (Secretin Family Receptors) Pathway Diagram
Endochondral Ossification Pathway antibodies	Endochondral Ossification Pathway Diagram
G Alpha (s) Signalling Events Pathway antibodies	G Alpha (s) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram

Organs/Tissues associated with PTHRP elisa kit

Organ/Tissue Name	Pubmed Publications
Other Antibodies	>222 publications with PTHRP and Other
Lung Antibodies	>132 publications with PTHRP and Lung
Skin Antibodies	>72 publications with PTHRP and Skin
Embryonic Tissue Antibodies	>62 publications with PTHRP and Embryonic Tissue
Mammary Gland Antibodies	>32 publications with PTHRP and Mammary Gland
Brain Antibodies	>28 publications with PTHRP and Brain
Ovary Antibodies	>15 publications with PTHRP and Ovary
Bladder Antibodies	>9 publications with PTHRP and Bladder
Extraembryonic Tissue Antibodies	>5 publications with PTHRP and Extraembryonic Tissue
Thymus Antibodies	>4 publications with PTHRP and Thymus