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MTA2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS435102

This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
MTA2, Monoclonal Antibody
Full Product Name
MTA2 Mouse mAb
Product Gene Name
anti-MTA2 antibody
Product Synonym Gene Name
MTA1-L1; MTA1L1
Clonality
Monoclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Preparation and Storage
Store at -20 degree C. Stable for one year from the date of shipment.
Molecular Weight
Predicted MW: 75kDa
3D Structure
ModBase 3D Structure for O94776
Source Note
This monoclonal antibody is produced by immunizing mice with a sythetic peptide(KLH coupled)corresponding to amino-terminal residues of human MTA2

Product Categories/Family for anti-MTA2 antibody

Cell Marker; Subcellular Marker; Nucleoplasma
Applications Tested/Suitable for anti-MTA2 antibody
Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
Application Notes for anti-MTA2 antibody
WB: 1:1000-1:5000
IP: 10 tests
FC/FACS: 1:100-1:200

Western Blot (WB) of anti-MTA2 antibody

Mouse Anti-MTA2 Monoclonal Antibody – Cat# MBS435102

Immunoprecipitation (IP) of anti-MTA2 antibody

MTA was immunoprecipitated from 1mg of Jurkat cells membrane fraction, blotted with M25055 of 10 ug. Western blot was performed from the immunoprecipitate using M25055 at 1/2000 dilution. Anti-Mouse-IgG(HRP), specific to the non-reduced form of IgG, was used as secondary antibody at 1/10000 dilution. Lane 1: Jurkat cells membrane fraction. Lane2: IP product of Jurkat cells membrane fraction.

Blocking and dilution buffer and concentration:5% milk/TBST.
Mouse Anti-MTA2 Monoclonal Antibody, Immunoprecipitation (IP) – Cat# MBS435102

Flow Cytometry (FC/FACS) of anti-MTA2 antibody

Flow cytometric analysis of 2% paraformaldehyde-fixed Jurkat (Human T cell leukemia cells from peripheral blood) cells labeling MTA with M25055 at 1/200 dilution (green) compared with a mouse monoclonal IgG isotype control (black) and an unlabelled control (cells without incubation with primary antibody, red). Goat anti-mouse IgG (FITC) at 1/300 dilution was used as the secondary antibody.All lanes : MTA Mouse mAb at 1/2000 dilution
Lane 1 : Jurkat cells membrane fraction
Lane 2 : THP1 cells membrane fraction
Lysates/proteins at 20 ug per lane.

Secondary
Goat Anti-Mouse IgG-HRP, 5%milk conjugated at 1/10000 dilution

Predicted band size : 75 KDa
Observed band size : 75 KDa
Blocking/Dilution buffer : 1x TBST.
Mouse Anti-MTA2 Monoclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS435102

Other Notes

Small volumes of anti-MTA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MTA2 purchase

MBS435102 is an antibody targeting MTA2. Also known as MTA2 Mouse mAb. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for MTA2. It may not necessarily be applicable to this product.

NCBI GI #
1060099369
NCBI GeneID
9219
NCBI Accession #
NP_001317221.1
UniProt Primary Accession #
O94776
UniProt Secondary Accession #
Q68DB1; Q9UQB5
UniProt Related Accession #
O94776
GenBank Nucleotide #
NM_001330292.1
NCBI Official Full Name
metastasis-associated protein MTA2 isoform 2
NCBI Official Synonym Full Names
metastasis associated 1 family member 2
NCBI Official Symbol
MTA2
NCBI Official Synonym Symbols
PID; MTA1L1
UniProt Protein Name
Metastasis-associated protein MTA2
UniProt Synonym Protein Names
Metastasis-associated 1-like 1; MTA1-L1 protein; p53 target protein in deacetylase complex
Protein Family
Metastasis-associated protein
UniProt Gene Name
MTA2
UniProt Synonym Gene Names
MTA1L1; PID; MTA1-L1 protein
NCBI Protein Information
metastasis-associated protein MTA2

UniProt Comments for MTA2

May be involved in the regulation of gene expression as repressor and activator. The repression might be related to covalent modification of histone proteins.

Research Articles on MTA2

1. This study is the first to demonstrate that SNHG5 is a critical and powerful regulator that is involved in GC progression through trapping MTA2 in the cytosol.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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